ISOLATION, STRUCTURAL IDENTIFICATION AND BIOLOGICAL ACTIVITY OF TWO METABOLITES PRODUCED BY Penicillium olsonii BAINIER AND SARTORY

From the culture broth of a fungus, two metabolites have been isolated: bis(2-ethylhexyl) phthalate (DEHP) precedently isolated from Streptomyces sp. and 2-(4-hydroxyphenyl)-2-oxoacetaldehyde oxime (PHBA) here reported as a natural compound in the (E)-s-cis configuration. The producing organism was...

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Bibliographic Details
Published inJournal of antibiotics Vol. 47; no. 2; pp. 201 - 208
Main Authors AMADE, P., MALLEA, M., BOUAÏCHA, N.
Format Journal Article
LanguageEnglish
Published Tokyo JAPAN ANTIBIOTICS RESEARCH ASSOCIATION 1994
Japan Antibiotics Research Association
Subjects
Biological and medical sciences
Diethylhexyl Phthalate - isolation & purification
General pharmacology
Magnetic Resonance Spectroscopy
Medical sciences
Microbial Sensitivity Tests
Oximes - chemistry
Oximes - isolation & purification
Oximes - pharmacology
Penicillium - metabolism
Penicillium olsonii
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phenols - chemistry
Phenols - isolation & purification
Phenols - pharmacology
Stereoisomerism
Streptomyces
Fungi
Microbial origin
Penicillium
Metabolite
Isolation
Oxime
Fungi Imperfecti
Biological activity
Thallophyta
Structural analysis
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Summary:From the culture broth of a fungus, two metabolites have been isolated: bis(2-ethylhexyl) phthalate (DEHP) precedently isolated from Streptomyces sp. and 2-(4-hydroxyphenyl)-2-oxoacetaldehyde oxime (PHBA) here reported as a natural compound in the (E)-s-cis configuration. The producing organism was identified as a strain of Penicillium olsonii. Culture growth and chemical identification are discussed in the present work.
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ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.47.201