Intrauterine growth retardation in foetuses of women with epilepsy

Highlights • We identified impaired intrauterine growth of foetuses in women with epilepsy. • Significantly higher risk of low ponderal index and small for gestational age (SGA). • Exposure to anti epileptic drugs increased the risk of SGA. • SGA and low ponderal index was most frequent in Lamictal...

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Published inSeizure (London, England) Vol. 28; pp. 76 - 80
Main Authors Farmen, Anette Huuse, Grundt, Jacob, Tomson, Torbjörn, Nakken, Karl Otto, Nakling, Jakob, Mowinchel, Petter, Lossius, Morten
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.05.2015
Subjects
Adult
Anticonvulsants - adverse effects
Birth Weight
Congenital Abnormalities - epidemiology
Congenital Abnormalities - etiology
Epilepsy - complications
Epilepsy - drug therapy
Female
Fetal Growth Retardation - chemically induced
Fetal Growth Retardation - epidemiology
Growth restriction
Humans
Longitudinal Studies
Maternal-Fetal Exchange
Medicin och hälsovetenskap
Neurology
Norway - epidemiology
Ponderal index
Pregnancy
Pregnancy Complications - chemically induced
Pregnancy in epilepsy
Prospective Studies
Risk Factors
Small for gestational age
Norway
Growth restriction
Ponderal index
Small for gestational age
Pregnancy in epilepsy
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Summary:Highlights • We identified impaired intrauterine growth of foetuses in women with epilepsy. • Significantly higher risk of low ponderal index and small for gestational age (SGA). • Exposure to anti epileptic drugs increased the risk of SGA. • SGA and low ponderal index was most frequent in Lamictal exposed infants.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1059-1311
1532-2688
1532-2688
DOI:10.1016/j.seizure.2015.02.026