White Matter Injury of Prematurity: Its Mechanisms and Clinical Features

A developing central nervous system is vulnerable to various insults such as infection and ischemia. While increased understanding of the dynamic nature of brain development allows a deeper insight into the pathophysiology of perinatal brain injury, the precise nature of specific fetal and neonatal...

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Bibliographic Details
Published inJournal of pathology and translational medicine Vol. 51; no. 5; pp. 449 - 455
Main Author Lee, Young Ah
Format Journal Article
LanguageEnglish
Published Korea (South) Korean Society of Pathologists, Korean Society for Cytopathology 01.09.2017
The Korean Society of Pathologists and the Korean Society for Cytopathology
Korean Society of Pathologists & the Korean Society for Cytopathology
대한병리학회
Subjects
Age
Attention Deficit Hyperactivity Disorder
Babies
Birth weight
Cerebral palsy
Gangrene
Hemorrhage
Hypoxia
Infections
Inflammation
Injury
Ischemia
Nervous system
Newborn babies
Periventricular leukomalacia
Preeclampsia
Pregnancy
Premature birth
Prematurity
Review
Risk factors
Traumatic brain injury
White matter
병리학
Periventricular leukomalacia
Prematurity
White matter
Injury
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Summary:A developing central nervous system is vulnerable to various insults such as infection and ischemia. While increased understanding of the dynamic nature of brain development allows a deeper insight into the pathophysiology of perinatal brain injury, the precise nature of specific fetal and neonatal brain injuries and their short- and long-term clinical consequences need special attention and further elucidation. The current review will describe the pathophysiological aspects and clinical significance of white matter injury of prematurity, a main form of perinatal brain injury in premature newborns, with a particular emphasis on its potential antenatal components.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:2383-7837
2383-7845
DOI:10.4132/jptm.2017.07.25