Protecting Effect of Phytoncide Solution, on Normal Human Dermal Fibroblasts against Reactive Oxygen Species

Four types of phytoncide solutions (A-Type, AB-Type, D-Type and G-Type) was evaluated for reduction of cell damage induced by oxidative stress, ultraviolet A (UVA), ultraviolet B (UVB), hydroxyperoxide (H2O2) and t-butyl-hydroperoxide (t-BHP); stimulation of collagen synthesis against UVA irradiatio...

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Published inJournal of Oleo Science Vol. 58; no. 8; pp. 429 - 436
Main Authors Fujimori, Hiroaki, Hisama, Masayoshi, Shibayama, Hiroharu, Iwaki, Masahiro
Format Journal Article
LanguageEnglish
Published Japan Japan Oil Chemists' Society 2009
Japan Science and Technology Agency
Subjects
collagen content
Dose-Response Relationship, Drug
Fibroblasts - drug effects
Fibroblasts - metabolism
Humans
Hydrogen Peroxide - pharmacology
Matrix Metalloproteinase 1 - metabolism
Matrix Metalloproteinase Inhibitors
matrix metalloproteinase-1 (MMP-1)
normal human dermal fibroblasts
oxidative stress
Oxidative Stress - drug effects
Phytoncide solution
Plant Extracts - pharmacology
Poaceae - chemistry
Reactive Oxygen Species - metabolism
Skin - cytology
Solutions
tert-Butylhydroperoxide - pharmacology
Ultraviolet Rays
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Abstract Four types of phytoncide solutions (A-Type, AB-Type, D-Type and G-Type) was evaluated for reduction of cell damage induced by oxidative stress, ultraviolet A (UVA), ultraviolet B (UVB), hydroxyperoxide (H2O2) and t-butyl-hydroperoxide (t-BHP); stimulation of collagen synthesis against UVA irradiation; and inhibition of matrix metalloproteinase-1 (MMP-1) activity induced by UVA in human normal dermal fibroblasts and human reconstituted skin model. The A-Type, AB-Type, D-Type and G-Type of phytoncide solutions pretreatment resulted in significant protection against cell damage induced by UVB, UVA, H2O2 and t-BHP. The amount of type I collagen following UVA irradiation was increased by treatment with phytoncide solutions in a concentration-dependent manner. On the other hand, phytoncide solutions also suppressed the excess MMP-1 irradiated UVA in a concentration-dependent manner. These effects of G-type solution were superior to those of other types solutions.
AbstractList Abstract: Four types of phytoncide solutions (A-Type, AB-Type, D-Type and G-Type) was evaluated for reduction of cell damage induced by oxidative stress, ultraviolet A (UVA), ultraviolet B (UVB), hydroxyperoxide (H2O2) and t-butyl-hydroperoxide (t-BHP); stimulation of collagen synthesis against UVA irradiation; and inhibition of matrix metalloproteinase-1 (MMP-1) activity induced by UVA in human normal dermal fibroblasts and human reconstituted skin model. The A-Type, AB-Type, D-Type and G-Type of phytoncide solutions pretreatment resulted in significant protection against cell damage induced by UVB, UVA, H2O2 and t-BHP. The amount of type I collagen following UVA irradiation was increased by treatment with phytoncide solutions in a concentration-dependent manner. On the other hand, phytoncide solutions also suppressed the excess MMP-1 irradiated UVA in a concentration-dependent manner. These effects of G-type solution were superior to those of other types solutions.
Four types of phytoncide solutions (A-Type, AB-Type, D-Type and G-Type) was evaluated for reduction of cell damage induced by oxidative stress, ultraviolet A (UVA), ultraviolet B (UVB), hydroxyperoxide (H2O2) and t-butyl-hydroperoxide (t-BHP); stimulation of collagen synthesis against UVA irradiation; and inhibition of matrix metalloproteinase-1 (MMP-1) activity induced by UVA in human normal dermal fibroblasts and human reconstituted skin model. The A-Type, AB-Type, D-Type and G-Type of phytoncide solutions pretreatment resulted in significant protection against cell damage induced by UVB, UVA, H2O2 and t-BHP. The amount of type I collagen following UVA irradiation was increased by treatment with phytoncide solutions in a concentration-dependent manner. On the other hand, phytoncide solutions also suppressed the excess MMP-1 irradiated UVA in a concentration-dependent manner. These effects of G-type solution were superior to those of other types solutions.
Author Fujimori, Hiroaki
Iwaki, Masahiro
Hisama, Masayoshi
Shibayama, Hiroharu
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Abstract: Four types of phytoncide solutions (A-Type, AB-Type, D-Type and G-Type) was evaluated for reduction of cell damage induced by oxidative stress,...
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SubjectTerms collagen content
Dose-Response Relationship, Drug
Fibroblasts - drug effects
Fibroblasts - metabolism
Humans
Hydrogen Peroxide - pharmacology
Matrix Metalloproteinase 1 - metabolism
Matrix Metalloproteinase Inhibitors
matrix metalloproteinase-1 (MMP-1)
normal human dermal fibroblasts
oxidative stress
Oxidative Stress - drug effects
Phytoncide solution
Plant Extracts - pharmacology
Poaceae - chemistry
Reactive Oxygen Species - metabolism
Skin - cytology
Solutions
tert-Butylhydroperoxide - pharmacology
Ultraviolet Rays
Title Protecting Effect of Phytoncide Solution, on Normal Human Dermal Fibroblasts against Reactive Oxygen Species
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