Small Microbial Genome: The End of a Long Symbiotic Relationship

Intracellular bacteria are characterized by genome reduction. The 422,434-base pair genome of Buchnera aphidicola BCc, primary endosymbiont of the aphid Cinara cedri, is ~200 kilobases smaller than the previously sequenced B. aphidicola genomes. B. aphidicola BCc has lost most metabolic functions, i...

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Published inScience (American Association for the Advancement of Science) Vol. 314; no. 5797; pp. 312 - 313
Main Authors Pérez-Brocal, Vicente, Gil, Rosario, Ramos, Silvia, Lamelas, Araceli, Postigo, Marina, Michelena, José Manuel, Silva, Francisco J, Moya, Andrés, Latorre, Amparo
Format Journal Article
LanguageEnglish
Published Washington, DC American Association for the Advancement of Science 13.10.2006
The American Association for the Advancement of Science
Subjects
Amino acid metabolism
Amino Acids - biosynthesis
Animals
Aphididae
Aphids - microbiology
Aphids - physiology
Bacteria
Bacteriocytes
Bacteriology
Base Pairing
Biological and medical sciences
Biosynthesis
Buchnera - genetics
Buchnera - metabolism
Buchnera - physiology
Buchnera aphidicola
Chromosomes, Bacterial - genetics
Cinara
Cinara cedri
Endosymbionts
Essential amino acids
Evolution
Evolution, Molecular
Fundamental and applied biological sciences. Psychology
Genes
Genes, Bacterial
Genetics
Genome, Bacterial
Genomes
Genomics
Insects
Microbiology
Molecular Sequence Data
Sequence Analysis, DNA
Sequencing
Serratia - genetics
Serratia - metabolism
Serratia - physiology
Symbiosis
Tryptophan - biosynthesis
Aphidoidea
Buchnera aphidicola
Insecta
Symbiont
Lachnidae
Intracellular symbiosis
Homoptera
Gene
Arthropoda
DNA
Bacteria
Invertebrata
Genome
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Summary:Intracellular bacteria are characterized by genome reduction. The 422,434-base pair genome of Buchnera aphidicola BCc, primary endosymbiont of the aphid Cinara cedri, is ~200 kilobases smaller than the previously sequenced B. aphidicola genomes. B. aphidicola BCc has lost most metabolic functions, including the ability to synthesize the essential amino acid tryptophan and riboflavin. In addition, most retained genes are evolving rapidly. Possibly, B. aphidicola BCc is losing its symbiotic capacity and is being complemented (and might be replaced) by the highly abundant coexisting secondary symbiont.
Bibliography:http://www.scienceonline.org/
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ISSN:0036-8075
1095-9203
DOI:10.1126/science.1130441