Advanced Strategies for Production of Natural Products in Yeast

• Published in: iScience Vol. 23; no. 3; p. 100879
• Main Authors: Chen, Ruibing, Yang, Shan, Zhang, Lei, Zhou, Yongjin J.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 27.03.2020; Elsevier
• Subjects: Bioengineering; Biological Sciences; Biotechnology; Metabolic Engineering; Microbial Biotechnology; Review; Bioengineering; Metabolic Engineering; Biological Sciences; Biotechnology; Microbial Biotechnology

Natural products account for more than 50% of all small-molecule pharmaceutical agents currently in clinical use. However, low availability often becomes problematic when a bioactive natural product is promising to become a pharmaceutical or leading compound. Advances in synthetic biology and metabo...