Changes in Mini Mental State Examination score after stroke: lacunar infarction predicts cognitive decline
Stroke and cognitive impairment are inter‐related. The purpose of this study was to show the natural evolution of cognitive performance during the first year after a stroke, and to show which factors that predict cognitive decline. Subjects were patients with a first‐ever stroke who were treated in...
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Published in | European journal of neurology Vol. 13; no. 5; pp. 491 - 495 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Oxford, UK
Blackwell Publishing Ltd
01.05.2006
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Subjects | |
Online Access | Get full text |
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Summary: | Stroke and cognitive impairment are inter‐related. The purpose of this study was to show the natural evolution of cognitive performance during the first year after a stroke, and to show which factors that predict cognitive decline. Subjects were patients with a first‐ever stroke who were treated in a stroke unit. A total of 160 patients were included. At baseline patients were evaluated with regard to stroke type, stroke severity, pre‐stroke dementia and other risk factors. Mini Mental State Examinations (MMSE) were performed after 1 week and after 1 year. Patients had a median increase of 1 point (range −8 to +9) on the MMSE. Thirty‐two pre cent of the patients deteriorated, 13% were unchanged, and 55% improved. Lacunar infarction (LI) and left‐sided stroke were associated with a failure to exhibit improvement. Patients with LI had an average decline of 1.7 points, whilst patients with other stroke types had an average increase of 1.8 points. Most stroke survivors improve cognitively during the first year after the event. The outcome for LI patients is worse, which suggests that LI may serve as a marker for concomitant processes that cause cognitive decline. |
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Bibliography: | ArticleID:ENE1299 ark:/67375/WNG-5TW8DNG2-2 istex:CC7E03C71A0AD46E770C0B6615831087D7251C57 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1351-5101 1468-1331 1468-1331 |
DOI: | 10.1111/j.1468-1331.2006.01299.x |