Microbial Hyaluronic Acid Production: A Review

Microbial production of hyaluronic acid (HA) is an area of research that has been gaining attention in recent years due to the increasing demand for this biopolymer for several industrial applications. Hyaluronic acid is a linear, non-sulfated glycosaminoglycan that is widely distributed in nature a...

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Published inMolecules (Basel, Switzerland) Vol. 28; no. 5; p. 2084
Main Authors Serra, Mónica, Casas, Ana, Toubarro, Duarte, Barros, Ana Novo, Teixeira, José António
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 23.02.2023
MDPI
Subjects
Acetylglucosamine
Acid production
Biocompatibility
Biopolymers
Cell growth
Chemical Phenomena
Cosmetics
E coli
Fermentation
Glucuronic Acid
Glycosaminoglycans
Gram-positive bacteria
Hyaluronic Acid
Hydration
Industrial applications
Lubricants & lubrication
Medical equipment
Methods
microbial production
Microorganisms
Molecular weight
N-Acetylglucosamine
Physiological aspects
Review
Skin
Viscoelasticity
Portugal
fermentation
microbial production
hyaluronic acid
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Summary:Microbial production of hyaluronic acid (HA) is an area of research that has been gaining attention in recent years due to the increasing demand for this biopolymer for several industrial applications. Hyaluronic acid is a linear, non-sulfated glycosaminoglycan that is widely distributed in nature and is mainly composed of repeating units of N-acetylglucosamine and glucuronic acid. It has a wide and unique range of properties such as viscoelasticity, lubrication, and hydration, which makes it an attractive material for several industrial applications such as cosmetics, pharmaceuticals, and medical devices. This review presents and discusses the available fermentation strategies to produce hyaluronic acid.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules28052084