慢性髓性白血病患者CD34＋细胞BCR-ABL融合基因的检测意义
慢性髓性白血病（CML）是一种起源于造血干细胞的恶性克隆性疾病。其特征性标志是Ph染色体及BCR—ABL融合基因。酪氨酸激酶抑制剂（TKI）作为CML患者靶向治疗药物，极大程度提高了CML患者的临床疗效，现已成为CML临床一线治疗药物。...
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| Published in | 中华血液学杂志 Vol. 38; no. 2; pp. 164 - 166 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
450008,郑州大学附属肿瘤医院(河南省肿瘤医院)血液科
2017
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0253-2727 |
| DOI | 10.3760/cma.j.issn.0253-2727.2017.02.016 |
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| Abstract | 慢性髓性白血病（CML）是一种起源于造血干细胞的恶性克隆性疾病。其特征性标志是Ph染色体及BCR—ABL融合基因。酪氨酸激酶抑制剂（TKI）作为CML患者靶向治疗药物，极大程度提高了CML患者的临床疗效，现已成为CML临床一线治疗药物。 |
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| AbstractList | @@ 慢性髓性白血病（CML）是一种起源于造血干细胞的恶性克隆性疾病。其特征性标志是Ph染色体及BCR—ABL融合基因。酪氨酸激酶抑制剂（TKI）作为CML患者靶向治疗药物，极大程度提高了CML患者的临床疗效，现已成为CML临床一线治疗药物。 |
| Author | 马轶轩 王璐 米瑞华 王献伟 吕晓东 范瑞华 魏旭东 |
| AuthorAffiliation | 郑州大学附属肿瘤医院河南省肿瘤医院血液科,450008 |
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| Author_FL | Lyu Xiaodong Fan Ruihua Wei Xudong Mi Ruihua Wang Lu Ma Yixuan Wang Xianwei |
| Author_FL_xml | – sequence: 1 fullname: Ma Yixuan – sequence: 2 fullname: Wang Lu – sequence: 3 fullname: Mi Ruihua – sequence: 4 fullname: Wang Xianwei – sequence: 5 fullname: Lyu Xiaodong – sequence: 6 fullname: Fan Ruihua – sequence: 7 fullname: Wei Xudong |
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| DOI | 10.3760/cma.j.issn.0253-2727.2017.02.016 |
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| DocumentTitleAlternate | Significance of BCR-ABL fusion gene detection in CD34＋ cells of chronic myelogenous leukemia patients |
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| Notes | 12-1090/R Ma Yixu- an, Wang Lu, Mi Ruihua, Wang Xianwei, Lyu Xiaodong, Fan Ruihua, Wei Xudong（ Department of Hematolo- gy, the Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou 450008, China. ） |
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| Snippet | 慢性髓性白血病（CML）是一种起源于造血干细胞的恶性克隆性疾病。其特征性标志是Ph染色体及BCR—ABL融合基因。酪氨酸激酶抑制剂（TKI）作为CML患者靶向治疗药物，极大程度提高了CML患者的临床疗效，现已成为CML临床一线治疗药物。 @@ |
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| SubjectTerms | BCR-ABL融合基因 CD34＋细胞 恶性克隆性疾病 慢性髓性白血病 检测 白血病患者 酪氨酸激酶抑制剂 靶向治疗药物 |
| Title | 慢性髓性白血病患者CD34＋细胞BCR-ABL融合基因的检测意义 |
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