Structural identifiability analysis of a cardiovascular system model
Highlights • We show that lumped-parameter models of the cardiovascular system have non-identifiability issues. • We present a clinically available output set and demonstrate that the cardiovascular system model of interest is identifiable from this output set. • We show that with a supplementary as...
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Published in | Medical engineering & physics Vol. 38; no. 5; pp. 433 - 441 |
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Main Authors | , , , , , |
Format | Journal Article Web Resource |
Language | English |
Published |
England
Elsevier Ltd
01.05.2016
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | Highlights • We show that lumped-parameter models of the cardiovascular system have non-identifiability issues. • We present a clinically available output set and demonstrate that the cardiovascular system model of interest is identifiable from this output set. • We show that with a supplementary assumption, this output set can be further reduced. • This analysis implies that the parameter identification procedure can theoretically be performed. • Thus, the model may be considered suitable for use in diagnosis. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 scopus-id:2-s2.0-84959906857 |
ISSN: | 1350-4533 1873-4030 1873-4030 |
DOI: | 10.1016/j.medengphy.2016.02.005 |