Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Induces Caspase-Dependent Interleukin-8 Expression and Apoptosis in Human Astroglioma Cells

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Published inMolecular and Cellular Biology Vol. 22; no. 3; pp. 724 - 736
Main Authors Choi, Chulhee, Kutsch, Olaf, Park, Jinseu, Zhou, Tong, Seol, Dai-Wu, Benveniste, Etty N.
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 01.02.2002
Taylor & Francis
Subjects
Antibodies, Monoclonal - pharmacology
Apoptosis
Apoptosis Regulatory Proteins
Astrocytoma - genetics
Astrocytoma - pathology
Astrocytoma - physiopathology
Brain Neoplasms - genetics
Brain Neoplasms - pathology
Brain Neoplasms - physiopathology
Caspase 3
Caspases - metabolism
Cell Growth and Development
Enzyme Activation
Humans
Interleukin-8 - biosynthesis
Interleukin-8 - genetics
Membrane Glycoproteins - antagonists & inhibitors
Membrane Glycoproteins - genetics
Membrane Glycoproteins - physiology
Models, Biological
Receptors, TNF-Related Apoptosis-Inducing Ligand
Receptors, Tumor Necrosis Factor - antagonists & inhibitors
Receptors, Tumor Necrosis Factor - genetics
Receptors, Tumor Necrosis Factor - physiology
RNA, Messenger - genetics
RNA, Messenger - metabolism
RNA, Neoplasm - genetics
RNA, Neoplasm - metabolism
Signal Transduction
TNF-Related Apoptosis-Inducing Ligand
TRAIL protein
Transfection
Tumor Cells, Cultured
Tumor Necrosis Factor-alpha - antagonists & inhibitors
Tumor Necrosis Factor-alpha - genetics
Tumor Necrosis Factor-alpha - physiology
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Present address: Department of Genetic Engineering, Division of Life Science, College of Natural Science, Hallym University, Chunchon 200-702, Korea.
Corresponding author. Mailing address: Department of Cell Biology, MCLM 386, University of Alabama at Birmingham, 1918 University Blvd., Birmingham, AL 35294-0005. Phone: (205) 934-7668. Fax: (205) 975-5648. E-mail: cchoi@uab.edu.
ISSN:0270-7306
1098-5549
1098-5549
DOI:10.1128/MCB.22.3.724-736.2002