Rheumatoid Arthritis: A Brief Overview of the Treatment

Rheumatoid arthritis (RA) is a chronic, inflammatory, systemic autoimmune disease, affecting the joints with varying severity among patients. The risk factors include age, gender, genetics, and environmental exposure (cigarette smoking, air pollutants, and occupational). Many complications can follo...

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Published inMedical principles and practice Vol. 27; no. 6; pp. 501 - 507
Main Authors Bullock, Jacqueline, Rizvi, Syed A.A., Saleh, Ayman M., Ahmed, Sultan S., Do, Duc P., Ansari, Rais A., Ahmed, Jasmin
Format Journal Article
LanguageEnglish
Published Basel, Switzerland S. Karger AG 01.01.2018
Subjects
Adrenal Cortex Hormones - adverse effects
Adrenal Cortex Hormones - therapeutic use
Analgesics
Analgesics, Opioid - therapeutic use
Anti-Inflammatory Agents, Non-Steroidal - adverse effects
Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
Antibodies, Monoclonal, Humanized - therapeutic use
Antirheumatic Agents - adverse effects
Antirheumatic Agents - therapeutic use
Arthritis, Rheumatoid - complications
Arthritis, Rheumatoid - drug therapy
Arthritis, Rheumatoid - surgery
Aspirin
Autoimmune diseases
Drug dosages
Exercise
Gene expression
Humans
Immunosuppressive Agents - therapeutic use
Inflammation
Interleukin 1 Receptor Antagonist Protein - therapeutic use
Joint surgery
Leflunomide - therapeutic use
Mini Review
Narcotics
Nonsteroidal anti-inflammatory drugs
Nurse specialists
Pain
Patients
Physical fitness
Physical Therapy Modalities
Rheumatoid arthritis
Risk Factors
Tumor Necrosis Factor-alpha - therapeutic use
Boutonnière deformity
Rheumatoid arthritis
Swan neck deformity
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Summary:Rheumatoid arthritis (RA) is a chronic, inflammatory, systemic autoimmune disease, affecting the joints with varying severity among patients. The risk factors include age, gender, genetics, and environmental exposure (cigarette smoking, air pollutants, and occupational). Many complications can follow, such as permanent joint damage requiring arthroplasty, rheumatoid vasculitis, and Felty syndrome requiring splenectomy if it remains unaddressed. As there is no cure for RA, the treatment goals are to reduce the pain and stop/slow further damage. Here, we present a brief summary of various past and present treatment modalities to address the complications associated with RA.
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ISSN:1011-7571
1423-0151
DOI:10.1159/000493390