Antithetical Effects of MicroRNA Molecules in Tuberculosis Pathogenesis
[1],[2] On the other hand, recent studies have revealed that infectious disease can induce microRNA (miRNA) molecule responses, for example, MiR-155 in Helicobacter pylori infection, let-7 family in Salmonella infection, and particularly, MiR-29 in mice infected with BCG vaccine. Overall, they impre...
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Published in | Advanced biomedical research Vol. 8; no. 1; p. 3 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
India
Medknow Publications and Media Pvt. Ltd
01.01.2019
Medknow Publications & Media Pvt. Ltd Medknow Publications & Media Pvt Ltd Wolters Kluwer Medknow Publications |
Subjects | |
Online Access | Get full text |
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Summary: | [1],[2] On the other hand, recent studies have revealed that infectious disease can induce microRNA (miRNA) molecule responses, for example, MiR-155 in Helicobacter pylori infection, let-7 family in Salmonella infection, and particularly, MiR-29 in mice infected with BCG vaccine. Overall, they impress various cell functions including cell proliferation and differentiation, DNA repair system, DNA modification (e.g. DNA methylation), apoptosis, and particularly, anti-inflammatory signaling pathways. PKA has pivotal roles on the cellular immune system, for example, activation of mitogen-activated protein kinase and induction of apoptotic pathway in MTB-infected macrophages. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 2277-9175 2277-9175 |
DOI: | 10.4103/abr.abr_217_18 |