基质辅助NMR中色谱技术的研究进展
被誉为＂NMR中色谱技术＂的二维扩散排序NMR谱（DOSY）技术是检测混合物溶液中不同分子组分的一种有效手段.但是当面对自扩散系数差别较小的不同分子时,DOSY技术便无法对上述混合物进行基线分离.在NMR魔角旋转转子或NMR样品管中添加一些色谱填料或高分子等基质（或称为虚拟＂色谱固定相＂）是一种行之有效的手段.这些虚拟＂色谱固定相＂与混合物组分发生相互作用并改变其自扩散系数,从而对混合物实现基线分离.该文综述了近年来基质辅助NMR中色谱技术的研究进展....
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| Published in | 波谱学杂志 Vol. 32; no. 4; pp. 699 - 706 |
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| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
中国烟草总公司郑州烟草研究院,河南郑州,450001%武汉工程大学化学与环境工程学院,湖北武汉,430073%中国科学院青岛生物能源与过程研究所，中国科学院生物基材料重点实验室，山东青岛266101
2015
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1000-4556 |
| DOI | 10.11938/cjmr20150415 |
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| Summary: | 被誉为＂NMR中色谱技术＂的二维扩散排序NMR谱（DOSY）技术是检测混合物溶液中不同分子组分的一种有效手段.但是当面对自扩散系数差别较小的不同分子时,DOSY技术便无法对上述混合物进行基线分离.在NMR魔角旋转转子或NMR样品管中添加一些色谱填料或高分子等基质（或称为虚拟＂色谱固定相＂）是一种行之有效的手段.这些虚拟＂色谱固定相＂与混合物组分发生相互作用并改变其自扩散系数,从而对混合物实现基线分离.该文综述了近年来基质辅助NMR中色谱技术的研究进展. |
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| Bibliography: | HE Bao-jiang, XU Xiu-juan, YANG Wei-ping, ZHANG Wen-juan, WU Rui, HUANG Shao-hua, YANG Ying, BAI Zheng-wu （1. Zhengzhou Tobacco Institute of CNTC, Zhengzhou 450001, China; 2. Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China; School of Chemical and Environment Engineering, Wuhan Institute of Technology, Wuhan 430073, China） 42-1180/O4 Diffusion ordered NMR spectroscopy（DOSY）, sometimes also known as chromatographic NMR（CNMR）, is a powerful tool for analyzing complex mixture. However, it is often difficult to distinguish components having similar molecular properties using only the diffusion characteristics. A practical way to solve this problem is adding some matrices, such as silica gel or polymers into magic angle spinning rotor or NMR tube, as the virtual stationary phase（VSP）, to increase the difference in diffusion rate among different components. Matrix aided CNMR has been shown to have improved discriminating |
| ISSN: | 1000-4556 |
| DOI: | 10.11938/cjmr20150415 |