Gabapentin Use in the Neonatal Intensive Care Unit

Gabapentin was used for the treatment of term and preterm infants with suspected visceral hyperalgesia caused by a variety of neurologic and gastrointestinal morbidities. Improved feeding tolerance and decreased irritability were seen, as well as decreased usage of opioids and benzodiazepines. Adver...

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Published inThe Journal of pediatrics Vol. 169; pp. 310 - 312
Main Authors Edwards, Laura, MD, DeMeo, Stephen, DO, Hornik, Chi D., PharmD, BCPS, Cotten, C. Michael, MD, MHS, Smith, P. Brian, MD, MPH, MHS, Pizoli, Carolyn, MD, PhD, Hauer, Julie M., MD, Bidegain, Margarita, MD, MHS-CL
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.02.2016
Subjects
Amines - administration & dosage
Amines - adverse effects
Analgesics - administration & dosage
Analgesics - adverse effects
Benzodiazepines - administration & dosage
Benzodiazepines - adverse effects
Cyclohexanecarboxylic Acids - administration & dosage
Cyclohexanecarboxylic Acids - adverse effects
Female
Gabapentin
gamma-Aminobutyric Acid - administration & dosage
gamma-Aminobutyric Acid - adverse effects
Humans
Hyperalgesia - drug therapy
Infant, Newborn
Intensive Care Units, Neonatal - statistics & numerical data
Male
Pediatrics
Retrospective Studies
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Summary:Gabapentin was used for the treatment of term and preterm infants with suspected visceral hyperalgesia caused by a variety of neurologic and gastrointestinal morbidities. Improved feeding tolerance and decreased irritability were seen, as well as decreased usage of opioids and benzodiazepines. Adverse events occurred with abrupt discontinuation of this medication.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2015.10.013