Prefrontal cortex dysfunction during cognitive tests evidenced by functional near-infrared spectroscopy

• Published in: Psychiatry research. Neuroimaging Vol. 171; no. 3; pp. 252 - 257
• Main Authors: Quaresima, Valentina, Giosuè, Patricia, Roncone, Rita, Casacchia, Massimo, Ferrari, Marco
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 31.03.2009; Elsevier
• Subjects: Adolescent; Adult; Adult and adolescent clinical studies; Attention - physiology; Biological and medical sciences; Cognition Disorders - diagnosis; Cognition Disorders - physiopathology; Dominance, Cerebral - physiology; Female; Humans; Male; Medical sciences; Memory, Short-Term - physiology; Middle Aged; Neuropsychological Tests - statistics & numerical data; Orientation - physiology; Oxygen Consumption - physiology; Pattern Recognition, Visual - physiology; Prefrontal Cortex - physiopathology; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychoses; Radiology; Schizophrenia; Schizophrenia - diagnosis; Schizophrenia - physiopathology; Spectroscopy, Near-Infrared; Verbal fluency test; Verbal Learning - physiology; Visual spatial working memory task; Young Adult; Schizophrenia; Visual spatial working memory task; Verbal fluency test; Human; Verbal fluency; Visual memory; Central nervous system; Cognition; Prefrontal cortex; Encephalon; Psychosis; Near infrared spectrometry; Working memory; Spatial memory
• ISSN: 0925-4927; 1872-7506
• DOI: 10.1016/j.pscychresns.2008.02.002

Prefrontal cortex oxygenation changes in response to a verbal fluency task and a visual spatial working memory task were investigated by functional near-infrared spectroscopy (fNIRS) on nine patients with schizophrenia. Four patients were reactive to both tests; five reactive to only one of the two tests, suggesting the importance of reporting fNIRS results for each individual.