Fourth human parechovirus serotype

We identified a novel human parechovirus (HPeV) type (K251176-02) from a neonate with fever. Analysis of the complete genome showed K251176-02 to be a new HPeV genotype. Since K251176-02 could not be neutralized with antibodies against known HPeV serotypes 1-3, it should be classified as a fourth HP...

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Bibliographic Details
Published inEmerging infectious diseases Vol. 12; no. 10; pp. 1572 - 1575
Main Authors Benschop, Kimberley S M, Schinkel, Janke, Luken, Manon E, van den Broek, Peter J M, Beersma, Matthias F C, Menelik, Negassi, van Eijk, Hetty W M, Zaaijer, Hans L, VandenBroucke-Grauls, Christina M J E, Beld, Marcel G H M, Wolthers, Katja C
Format Journal Article
LanguageEnglish
Published United States U.S. National Center for Infectious Diseases 01.10.2006
Centers for Disease Control and Prevention
Subjects
Base Sequence
Dispatch
full length genotyping
Genetic aspects
Genome, Viral
Genotype
Health aspects
HPeV serotype
Human parechovirus 4
Humans
Infant, Newborn
neutralization assay
Neutralization Tests
New human parechovirus genotype
Parechovirus - classification
Parechovirus - genetics
Parechovirus - isolation & purification
phylogenetic analysis
Picornaviridae Infections - virology
SimPlot analysis
Virus diseases
United States
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Summary:We identified a novel human parechovirus (HPeV) type (K251176-02) from a neonate with fever. Analysis of the complete genome showed K251176-02 to be a new HPeV genotype. Since K251176-02 could not be neutralized with antibodies against known HPeV serotypes 1-3, it should be classified as a fourth HPeV serotype.
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ISSN:1080-6040
1080-6059
DOI:10.3201/eid1210.051647