The measured effect magnitude of co-morbidities on burn injury mortality

• Published in: Burns Vol. 42; no. 7; pp. 1433 - 1438
• Main Authors: Knowlin, Laquanda, Stanford, Lindsay, Moore, Danier, Cairns, Bruce, Charles, Anthony
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.11.2016
• Subjects: Acquired Immunodeficiency Syndrome - epidemiology; Adolescent; Adult; Aged; Body Surface Area; Burn injury; Burn outcome; Burn Units; Burns - epidemiology; Burns - mortality; Cardiovascular Diseases - epidemiology; Charlson comorbidity index; Child; Child, Preschool; Comorbidity; Critical Care; Dementia - epidemiology; Diabetes Complications - epidemiology; Diabetes Mellitus - epidemiology; Female; Humans; Infant; Infant, Newborn; Kidney Diseases - epidemiology; LA50%TBSA; Length of Stay; Liver Diseases - epidemiology; Logistic Models; Lung Diseases - epidemiology; Male; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Neoplasms - epidemiology; Odds Ratio; Prognosis; Retrospective Studies; Smoke Inhalation Injury - epidemiology; Trauma Severity Indices; United States - epidemiology; Young Adult; LA50%TBSA; Burn outcome; Comorbidity; Burn injury; Charlson comorbidity index
• ISSN: 0305-4179; 1879-1409
• DOI: 10.1016/j.burns.2016.03.007

Highlights • The ability to better prognosticate burn injury outcome is challenging. • Historically, the weighted contribution of comorbidity on burn mortality has not been considered. • We utilize LA50%TBSA to assess the weighted contribution of comorbidities. • Comorbidities have a greater effect significant effect on the younger burn population. • Effect of comorbidities in the >65 yr age cohort was mitigated by co-linearity due to age.