Chronic suppurative otitis media in Nepal: ethnicity does not determine whether disease is associated with cholesteatoma or not

• Published in: Journal of laryngology and otology Vol. 125; no. 1; pp. 22 - 26
• Main Authors: Thornton, D, Martin, T P C, Amin, P, Haque, S, Wilson, S, Smith, M C F
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.01.2011
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Asian Continental Ancestry Group - statistics & numerical data; Bacterial diseases; Biological and medical sciences; Camps; Child; Child, Preschool; Cholesteatoma, Middle Ear - epidemiology; Cholesteatoma, Middle Ear - ethnology; Chronic Disease; Ear diseases; Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology; Ears & hearing; Ent and stomatologic bacterial diseases; Ethnicity; European Continental Ancestry Group - statistics & numerical data; Female; Human bacterial diseases; Humans; Infant; Infectious diseases; Male; Medical sciences; Middle Aged; Minority & ethnic groups; Names; Nepal - epidemiology; Nepal - ethnology; Non tumoral diseases; Odds Ratio; Otitis Media, Suppurative - epidemiology; Otitis Media, Suppurative - ethnology; Otology; Otorhinolaryngology. Stomatology; Patients; Regression analysis; Risk Factors; Tumors; White people; Young Adult; Asia; Nepal; Otitis Media, Suppurative; Ethnicity; Nepal; Chronic; Cholesteatoma; Middle ear disease; ENT disease; Tumor; Otitis media; ENT; Suppurative
• ISSN: 0022-2151; 1748-5460
• DOI: 10.1017/S0022215110001878

To determine the frequency of cholesteatoma in a population of patients with chronic suppurative otitis media, and to determine whether this frequency is affected by ethnicity. The study included 6005 patients with chronic suppurative otitis media seen during the course of 30 charitable surgical 'ear camps' in Nepal. Proportion of patients with each subtype of disease, and their ethnicity. A secondary outcome measure was concordance of surname with Nepalese ethnic affiliation. A total of 762 patients were grouped as being of Tibeto-Mongolian origin, and 4875 as Indo-Caucasian. The rate of chronic suppurative otitis media with cholesteatoma, expressed as a proportion of the rate of all chronic suppurative otitis media subtypes, was 17.8 per cent in Tibeto-Mongolian patients and 18.6 per cent in Indo-Caucasian patients (p > 0.05). The effect of other risk factors (i.e. age, gender and geographical district) on disease distribution was also non-significant. Analysis of secondary outcome measures indicated that patients' surnames were a reliable predictor of ethnicity in this Nepalese population. There is almost complete concordance in proportions of patients with significant genetic, cultural, and even geographical heterogeneity, suggesting that, in Nepal, the aetiology of cholesteatoma owes little to these factors.