Twin studies: A unique epidemiological tool

Twin studies are a special type of epidemiological studies designed to measure the contribution of genetics as opposed to the environment, to a given trait. Despite the facts that the classical twin studies are still being guided by assumptions made back in the 1920s and that the inherent limitation...

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Bibliographic Details
Published inIndian journal of community medicine Vol. 41; no. 3; pp. 177 - 182
Main Authors Sahu, Monalisha, Prasuna, Josyula
Format Journal Article
LanguageEnglish
Published India Wolters Kluwer - Medknow Publications 01.07.2016
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Medknow Publications & Media Pvt Ltd
Wolters Kluwer Medknow Publications
Subjects
Analysis
CME
Concordance rates
Epidemiology
Genetics
molecular studies
statistical analysis system (SAS)
twin registries
twin studies
molecular studies
Concordance rates
statistical analysis system (SAS)
twin registries
twin studies
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Summary:Twin studies are a special type of epidemiological studies designed to measure the contribution of genetics as opposed to the environment, to a given trait. Despite the facts that the classical twin studies are still being guided by assumptions made back in the 1920s and that the inherent limitation lies in the study design itself, the results suggested by earlier twin studies have often been confirmed by molecular genetic studies later. Use of twin registries and various innovative yet complex software packages such as the (SAS) and their extensions (e.g., SAS PROC GENMOD and SAS PROC PHREG) has increased the potential of this epidemiological tool toward contributing significantly to the field of genetics and other life sciences.
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ISSN:0970-0218
1998-3581
DOI:10.4103/0970-0218.183593