Colostrum management practices that improve the transfer of passive immunity in neonatal dairy calves: A scoping review

• Published in: PloS one Vol. 17; no. 6; p. e0269824
• Main Authors: Uyama, T, Kelton, D. F, Winder, C. B, Dunn, J, Goetz, H. M, LeBlanc, S. J, McClure, J. T, Renaud, D. L
• Format: Journal Article
• Language: English
• Published: San Francisco Public Library of Science 29.06.2022; Public Library of Science (PLoS)
• Subjects: Acidosis; Age; Biology and Life Sciences; Blood; Blood levels; Calves; Citation indexes; Cohort analysis; Colostrum; Cross-sectional studies; Dairy cattle; Evaluation; Feeding; Grey literature; Health aspects; Hypoxia; Immunity; Immunity (passive); Immunoglobulin G; Infants (Newborn); Institutional repositories; Medicine and Health Sciences; Milk; Neonates; Newborn babies; Physical Sciences; Research and Analysis Methods; Risk analysis; Risk factors; Seasons; Synthesis; Systematic review; Canada
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0269824

The objective of this scoping review was to describe the literature on the characteristics and management practices of colostrum feeding and their associations with the level of transfer of passive immunity (TPI) in dairy calves. Observational and experimental studies were searched in 5 electronic databases and 3 conference proceedings. Two reviewers independently screened primary studies, either analytic observational or experimental studies written in English. Studies on dairy or dual-purpose calves with passive immunity analyzed by blood sampling between 1 to 9 days of age were included. All studies had to compare at least one colostrum intervention or risk factor and their association with passive immunity. Of the 3,675 initially identified studies, 256 were included in this synthesis. One hundred and ninety-five were controlled trials, 57 were cohort studies, and 4 were cross-sectional studies. The effect of colostral quantity at first feeding was investigated in 30 controlled studies including studies that were comparable to each other. The effect of colostral quality was explored in 24 controlled studies with inconsistent criteria used to define the quality. The effect of the timing of first feeding of colostrum was investigated in 21 controlled studies, where the timing of feeding ranged widely from immediately after birth to 60 h of age. Only 4 controlled studies evaluated the relationship between bacterial load in the colostrum and TPI in dairy calves. Of the 256 total studies, 222 assessed blood IgG concentration while 107 measured blood total protein concentration. We identified a gap in knowledge on the association between passive immunity in dairy calves and the bacterial load in colostrum, or the timing of harvesting colostrum from the dam. A possible quantitative synthesis could be conducted among the studies that evaluated colostral quantity at the first feeding in relation to TPI in dairy calves.