A survival analysis of socio-demographic and clinical predictors among hospitalized COVID-19 patients in Southern Iran

• Published in: BMC infectious diseases Vol. 23; no. 1; p. 175
• Main Authors: Esfandiari, Atefeh, Kiani, Jamileh, Amiri, Batool, Mahmoodi, Marzieh, Abbasi, Fatemeh, Javanmardi, Erfan, Yazdanpanah, Ahmad, Akhlaghi, Allahkarm, Salari, Hedayat
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 22.03.2023; BioMed Central; BMC
• Subjects: Age; Bushehr; Cancer; Coronaviruses; COVID-19; COVID-19 - epidemiology; Cross-Sectional Studies; Data collection; Data entry; Death; Demographics; Demography; Epidemics; Fatalities; Female; Hemoptysis; Hospitalization; Hospitals; Humans; Infectious diseases; Intensive care; Iran; Iran - epidemiology; Kidney diseases; Kidneys; Laboratories; Male; Medical prognosis; Methods; Middle Aged; Mortality; Patients; Registry; Regression analysis; Retrospective Studies; Risk Factors; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Survival; Survival Analysis; Variables; Viral diseases; Viruses; Vital signs; Iran; Bushehr; COVID-19; Iran; Mortality; Registry; Survival; Risk factors
• ISSN: 1471-2334; 1471-2334
• DOI: 10.1186/s12879-023-08129-8

This study aimed to evaluate the socio-demographic, clinical, and laboratory risk factors in hospitalized COVID-19 patients during the first 6 months of the SARS-CoV-2 epidemic. This retrospective hospital-based cross-sectional study included all laboratory-confirmed cases of the COVID-19 virus that were admitted to the Shohadaye-Khalije-Fars Hospital in Bushehr, Iran, from February 22, 2020 to September 21, 2020. The patients' records were reviewed during the hospitalization period. The global COVID-19 clinical platform, i.e., the World Health Organization Rapid Case Report Form was used as the data collection tool. We conducted the survival analysis using the Kaplan-Meier and the Stepwise Cox regression analyses. The analysis included 2108 confirmed cases of COVID-19 with a mean age of 47.81 years (SD 17.78); 56.8% men, 43.2% women and 6.3% (n = 133) deaths. After adjustment, it was found that factors associated with an increased risk of death consisted of chronic kidney disease, intensive care unit admission, cancer, and hemoptysis. The 7-day survival rate was 95.8%, which decreased to 95.1%, 94.0%, and 93.8% on days 14, 21, and 28 of hospitalization, respectively. Older COVID-19 patients with manifestation of hemoptysis and a past medical history of chronic kidney disease and cancer, should be closely monitored to prevent disease deterioration and death, and also should be admitted to the intensive care unit.