Neutralizing and enhancing antibodies against SARS-CoV-2

The high transmissibility and rapid global spread of SARS-CoV-2 since 2019 has led to a huge burden on healthcare worldwide. Anti-SARS-CoV-2 neutralizing antibodies play an important role in not only protecting against infection but also in clearing the virus and are essential to providing long-term...

Full description

Saved in:
Bibliographic Details
Published inInflammation and Regeneration Vol. 42; no. 1; p. 58
Main Authors Liu, Yafei, Arase, Hisashi
Format Journal Article
LanguageEnglish
Published England BioMed Central 05.12.2022
BMC
Subjects
COVID-19 vaccines
Enhancing antibody
Infections
Monoclonal antibodies
Mutation
Neutralizing antibody
Pandemics
Proteins
Review
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Enhancing antibody
SARS-CoV-2
Neutralizing antibody
Online AccessGet full text

Cover

More Information
Summary:The high transmissibility and rapid global spread of SARS-CoV-2 since 2019 has led to a huge burden on healthcare worldwide. Anti-SARS-CoV-2 neutralizing antibodies play an important role in not only protecting against infection but also in clearing the virus and are essential to providing long-term immunity. On the other hand, antibodies against the virus are not always protective. With the emergence of SARS-CoV-2 immune escape variants, vaccine design strategies as well as antibody-mediated therapeutic approaches have become more important. We review some of the findings on SARS-CoV-2 antibodies, focusing on both basic research and clinical applications.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1880-9693
1880-8190
DOI:10.1186/s41232-022-00233-7