Synchronous Primary Adenocarcinoma of the Lung and Leiomyosarcoma of the Small Intestine

• Published in: Internal Medicine Vol. 39; no. 8; pp. 655 - 658
• Main Authors: TAKEMOTO, Yuji, KAWAHARA, Masaaki, YAMAMOTO, Satoru, IUCHI, Keiji, MORI, Takashi, UEDA, Einosuke, TSUCHIYAMA, Tessei, FURUSE, Kiyoyuki
• Format: Journal Article
• Language: English
• Published: Tokyo The Japanese Society of Internal Medicine 2000; Japanese Society of Internal Medicine
• Subjects: Adenocarcinoma - pathology; Biological and medical sciences; Gastroenterology. Liver. Pancreas. Abdomen; Humans; Intestinal Neoplasms - pathology; Intestinal Neoplasms - surgery; Intestinal Obstruction - etiology; Intestinal Obstruction - surgery; Intestine, Small; Leiomyosarcoma - pathology; Leiomyosarcoma - surgery; leiomyosarcoma of the small intestine; Lung Neoplasms - pathology; Male; Medical sciences; Middle Aged; Neoplasms, Multiple Primary - pathology; Neoplasms, Multiple Primary - surgery; Pneumology; pulmonary adenocarcinoma; spindle cells of metastatic lung cancer; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; synchronous tumor; Tumors; Tumors of the respiratory system and mediastinum; Adenocarcinoma; Human; Lung disease; Respiratory disease; Smooth muscle; Malignant tumor; Small intestine; Bronchopulmonary; Case study; Concomitant disease; Leiomyosarcoma; Digestive diseases; Bronchus disease; Intestinal disease
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.39.655

The occurrence of synchronous epithelial cancer of the lung and leiomyosarcoma of the small intestine is rare. We report here the case of a 62-year-old man with adenocarcinoma of the lung in clinical stage IIIB (T4NOMO). After two courses of chemotherapy (cisplatin, 80 mg/m2 and mitomycin C, 8 mg/m2) the patient developed symptoms of a small bowel obstruction. Palliative surgical resection was performed and a leiomyosarcoma of the small intestine was found and defined by an immunohistological study. The resection ameliorated the patient's symptoms. The patient died of disseminated adenocarcinoma 26 months following chemotherapy. (Internal Medicine 39: 655-658, 2000)