Protein degradation systems in platelets

• Published in: Thrombosis and haemostasis Vol. 110; no. 5; p. 920
• Main Authors: Kraemer, B F, Weyrich, A S, Lindemann, S
• Format: Journal Article
• Language: English
• Published: Germany 01.11.2013
• Subjects: Animals; Blood Platelets - metabolism; Cysteine Proteases - metabolism; Humans; Proteasome Endopeptidase Complex - metabolism; Proteolysis; Signal Transduction; calpain; proteasome; Platelets; protein degradation

Protein synthesis and degradation are essential processes that allow cells to survive and adapt to their surrounding milieu. In nucleated cells, the degradation and/or cleavage of proteins is required to eliminate aberrant proteins. Cells also degrade proteins as a mechanism for cell signalling and...