The risk of sensitization to furry animals in patients already sensitized to cat/dog: An in vitro evaluation using molecular-based allergy diagnostics

Present in vitro and previous in vivo4 data suggest that allergic sensitization to c/d increases the risk of sensitization to horse and mouse because of the presence of lipocalins. Because lipocalins show a certain degree of cross-reactivity,5 a similar finding for other furry animals is likely.

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Bibliographic Details
Published inJournal of allergy and clinical immunology Vol. 135; no. 6; pp. 1664 - 1666
Main Authors Liccardi, Gennaro, MD, Meriggi, Antonio, MD, Russo, Maria, PhD, Croce, Stefania, MS, Salzillo, Antonello, MD, Pignatti, Patrizia, PhD
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.06.2015
Elsevier Limited
Subjects
Allergens - immunology
Allergies
Allergy and Immunology
Animals
Asthma - diagnosis
Hair - immunology
Humans
Hypersensitivity - diagnosis
Mammals
Pets
Rhinitis, Allergic, Perennial - diagnosis
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Summary:Present in vitro and previous in vivo4 data suggest that allergic sensitization to c/d increases the risk of sensitization to horse and mouse because of the presence of lipocalins. Because lipocalins show a certain degree of cross-reactivity,5 a similar finding for other furry animals is likely.
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ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.03.021