Olfactory and taste dysfunction in COVID-19-incidence and recovery

• Published in: The Egyptian journal of otolaryngology Vol. 39; no. 1; pp. 18 - 8
• Main Authors: Singhal, Surinder K., Gupta, Nitin, Verma, Ravneet R., Sharma, Jyotika, Sah, Monali, Jain, Shivani, Kashyap, Diksha
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2023; Springer; Springer Nature B.V; SpringerOpen
• Subjects: Age; Ageusia; Anosmia; COVID-19; COVID-19 diagnostic tests; Fever; Gustatory; Health aspects; Infection; Medicine; Medicine & Public Health; Olfaction; Olfaction disorders; Original; Original Article; Otolaryngology; Patients; Sensory perception; Smell; Surgery; Taste; Taste disorders; COVID-19; Gustatory; Olfaction; Anosmia; Taste; Ageusia; Smell
• ISSN: 2090-8539; 1012-5574; 2090-8539
• DOI: 10.1186/s43163-023-00383-6

Background Olfactory and taste dysfunctions have been identified as prominent signs of COVID-19 infection. The data on its prevalence, time of onset, and recovery is highly variable. Objective The study was aimed at establishing the incidence of and the factors influencing smell and taste disorders in COVID-19-affected patients. Methodology Telephonic interviews were used to collect data on the symptoms of COVID-19-positive patients, with an emphasis on smell and taste disorders. Patients have severe disease and a history of illnesses that may affect olfaction or taste, and those unwilling to participate were excluded. Results A total of 1488 COVID-19-positive patients were identified. A total of 772 were included and interviewed, and their data were analysed. A total of 242 (31.3%) patients developed symptoms related to smell and/or taste. Anosmia (149) and ageusia (152) were the most common. Younger patients were more commonly affected ( p  = 0.0016). The presence and degree of smell symptoms and taste symptoms showed a small positive correlation ( r  = .234, p  < .001). A strong relationship was seen with fever ( r  = .825, p  < .001) and a significantly moderate relationship with breathing difficulty. There was no significant difference based on age or sex for the recovery of smell or taste sensations. There was a significant correlation between taste recovery and smell recovery times ( p  < 0.00001). Conclusion Smell and taste disorders, as early clinical symptoms of COVID-19, may have a diagnostic as well as a prognostic value. Treatment protocols for these patients are yet to be defined. A positive association between these symptoms and breathing difficulty was found, and we recommend COVID-19 testing and monitoring of symptoms for all patients with new-onset OTD symptoms. A combination of active enquiry about these symptoms, along with objective testing when the patients present with COVID-19 symptoms may help in better understanding of the pathophysiology and timely initiation of treatment.