Application of Platelet-Rich Fibrin and Bone Morphogenetic Protein for Full-Mouth Implant-Based Oral Rehabilitation in a Case of Mandibular Osteoradionecrosis

• Published in: Case reports in dentistry Vol. 2023; pp. 1 - 9
• Main Authors: Moaddabi, Amirhossein, Soltani, Parisa, Yazdani, Arman, Nikbakht, Mohammad Hossein, Amani Beni, Pardis, Modabber, Elahe, Iaculli, Flavia, Spagnuolo, Gianrico
• Format: Journal Article
• Language: English
• Published: Egypt Hindawi 30.05.2023; John Wiley & Sons, Inc; Wiley
• Subjects: Blood platelets; Bone morphogenetic proteins; Case Report; Case reports; Dental implants; Dental prosthetics; Fibrin; Head & neck cancer; Health aspects; Implant dentures; Jaw; Mandible; Metastasis; Metronidazole; Necrosis; Osteoradionecrosis; Platelets; Prostheses; Radiation; Radiation therapy; Radiotherapy; Rehabilitation; Surgeons; Surgery; Teeth; Trauma; Iran; South Korea
• ISSN: 2090-6447; 2090-6455
• DOI: 10.1155/2023/2449298

Osteoradionecrosis (ORN) is a debilitating complication following radiation therapy, which in the head and neck region, occurs most frequently in the mandible. Although ORN is rare, it is complex and multifactorial and requires appropriate management. Manipulation of bone in patients with head and neck cancers before radiotherapy can cause ORN. In this report, we aim to present successful insertion of four dental implants in the interforaminal segment combined with application of platelet-rich fibrin and bone morphogenetic protein in a 60-year-old male with stable ORN in the posterior regions of the mandible.