Quantification of Vocal Fold Vibration in Various Laryngeal Disorders Using High-Speed Digital Imaging

• Published in: Journal of voice Vol. 30; no. 2; pp. 205 - 214
• Main Authors: Yamauchi, Akihito, Yokonishi, Hisayuki, Imagawa, Hiroshi, Sakakibara, Ken-Ichi, Nito, Takaharu, Tayama, Niro, Yamasoba, Tatsuya
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2016; Elsevier Science Ltd
• Subjects: Adult; Aged; Aged, 80 and over; Biomechanical Phenomena; Cancer; Carcinoma - diagnostic imaging; Carcinoma - physiopathology; Case-Control Studies; Female; High-speed digital imaging; Humans; Image Interpretation, Computer-Assisted; Kymography; Laryngeal cancer; Laryngeal granuloma; Laryngeal leukoplakia; Laryngeal Neoplasms - diagnostic imaging; Laryngeal Neoplasms - physiopathology; Laryngeal papilloma; Laryngology; Leukoplakia - diagnostic imaging; Leukoplakia - physiopathology; Male; Middle Aged; Otolaryngology; Patients; Phonation; Polyps - diagnostic imaging; Polyps - physiopathology; Predictive Value of Tests; Quantitative analysis; Reinke edema; Severity of Illness Index; Stroboscopy; Time Factors; Vibration; Vocal Cords - diagnostic imaging; Vocal Cords - physiopathology; Vocal fold cyst; Vocal fold nodule; Vocal fold polyp; Vocal folds; Voice disorders; Laryngeal cancer; Laryngeal leukoplakia; High-speed digital imaging; Reinke edema; Vocal fold cyst; Laryngeal granuloma; Laryngeal papilloma; Vocal fold polyp; Vocal fold nodule
• ISSN: 0892-1997; 1873-4588
• DOI: 10.1016/j.jvoice.2015.04.016

Summary Objective To quantify vibratory characteristics of various laryngeal disorders seen by high-speed digital imaging (HSDI). Methods HSDI was performed on 78 patients with various laryngeal disorders (20 with polyp, 16 with carcinoma, 13 with leukoplakia, 6 with vocal fold nodule, and 33 with others) and 29 vocally healthy subjects. Obtained data were quantitatively evaluated by frame-by-frame analysis, laryngotopography, digital kymography, and glottal area waveform. Results Overall, patients with laryngeal pathologies showed greater asymmetry in amplitude, mucosal wave and phase, smaller mucosal wave, and poorer glottal closure than vocally healthy subjects. Furthermore, disease-specific vibratory disturbances that generally agreed with the findings in the literature were quantified: comparing polyp with nodule, differences were noted in longitudinal phase difference, amplitude, and mucosal wave. In comparison with leukoplakia and cancer, nonvibrating area was more frequently noted in cancer. Conclusions The HSDI analysis of various voice disorders using multiple methods can help phonosurgeons to properly diagnose various laryngeal pathologies and to estimate the degree of their vocal disturbances.