Graphene‐Based Antimicrobial Biomedical Surfaces

• Published in: Chemphyschem Vol. 22; no. 3; pp. 250 - 263
• Main Authors: Pandit, Santosh, Gaska, Karolina, Kádár, Roland, Mijakovic, Ivan
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 03.02.2021; John Wiley and Sons Inc
• Subjects: Antibacterial materials; antimicrobial; Antimicrobial agents; Biocompatibility; biofilms; biomedical devices; Biomedical materials; Biosensors; Coatings; Derivatives; Graphene; graphene derivatives; Mechanical properties; Minireview; Minireviews; Nanocomposites; Tissue engineering; biomedical devices; antimicrobial; graphene derivatives; biocompatibility; biofilms
• ISSN: 1439-4235; 1439-7641; 1439-7641
• DOI: 10.1002/cphc.202000769

Biomedical application of graphene derivatives have been intensively studied in last decade. With the exceptional structural, thermal, electrical, and mechanical properties, these materials have attracted immense attention of biomedical scientists to utilize graphene derivatives in biomedical devices to improve their performance or to achieve desired functions. Surfaces of graphene derivatives including graphite, graphene, graphene oxide and reduce graphene oxide have been demonstrated to pave an excellent platform for antimicrobial behavior, enhanced biocompatibility, tissue engineering, biosensors and drug delivery. This review focuses on the recent advancement in the research of biomedical devices with the coatings or highly structured polymer nanocomposite surfaces of graphene derivatives for antimicrobial activity and sterile surfaces comprising an entirely new class of antibacterial materials. Overall, we aim to highlight on the potential of these materials, current understanding and knowledge gap in the antimicrobial behavior and biocompatibility to be utilized of their coatings to prevent the cross infections. Recent advances in the research of biomedical devices with coatings or highly structured polymer nanocomposites composed of graphene derivatives for self‐cleaning surfaces are reviewed. Overall, the authors aim to highlight the potential of these materials as well as the current understanding and knowledge gaps regarding their antimicrobial behavior and biocompatibility for use as biomedical coatings to prevent cross infections.