Management of symptomatic caliceal diverticular calculi:Minimally invasive percutaneous nephrolithotomy versus flexible ureterorenoscopy
Objective: To retrospectively evaluate appropriate treatment for patients with symptomatic caliceal diverticular calculi, by comparing the therapeutic outcomes for those undergoing minimally invasive percutaneous nephrolithotomy (MPCNL) and flexible ureterorenoscopy (F-URS). Methods: From March 2009...
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Published in | Chronic diseases and translational medicine Vol. 2; no. 4; pp. 250 - 256 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | Chinese English |
Published |
China
Elsevier B.V
01.12.2016
Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, China%Department of Clinical Medicine, Luohe Medical College, Luohe, Henan 462002, China%Department of Toxicology, School of Radiation Medicine and Public Health, Soochow University, Suzhou, Jiangsu 215123, China KeAi Publishing Wiley |
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Summary: | Objective: To retrospectively evaluate appropriate treatment for patients with symptomatic caliceal diverticular calculi, by comparing the therapeutic outcomes for those undergoing minimally invasive percutaneous nephrolithotomy (MPCNL) and flexible ureterorenoscopy (F-URS). Methods: From March 2009 to May 2014, 36 consecutive patients with caliceal diverticular calculi were divided into 2 groups:21 patients underwent MPCNL, and 15 were treated by F-URS. All procedures were performed by one surgical group, which ensured relatively constant parameters. Patient characteristics, operative time, hospital stay after surgery, stone-free rate, symptomatic improvement rate, complications, diverticular obliteration, and stone composition were analyzed retrospectively in the 2 groups. Results: Patient preoperative variables were comparable between the two groups, with no significant difference (P>0.05). Mean operative time was 136.9 ± 22.8 min in the MPCNL group and 117.3 ± 24.3 min in the F-URS group (P ? 0.019). Hospital stay was significantly longer in the MPCNL group than in the F-URS group (9.4 ± 3.1 vs. 6.9 ± 2.1 days, P ? 0.010). The stone-free rates after MPCNL and F-URS were 90.5%(19/21) and 60.0%(9/15), respectively (P ? 0.046). Additionally, 71.4%(15/21) of patients in the MPCNL group and 46.7%(7/15) of patients in the F-URS group had symptomatic improvement at the 6-month follow-up (P ? 0.175);the rates of complications in the 2 groups were 19.0%(4/21) and 13.3%(2/15), respectively (P ? 0.650). Complete diverticular obliteration was achieved in 16 (76.2%) cases in the MPCNL group and 5 (33.3%) cases in the F-URS group (P ? 0.017). The distributions of calcium oxalate and hydroxyapatite in the stones were 66.7% (14/21) and 33.3% (7/21), respectively, in the MPCNL group;however, the distributions in the F-URS group were 46.7%(7/15) and 53.3%(8/15), respec-tively (P ? 0.310). Conclusion: MPCNL is an effective method for the treatment of caliceal diverticular calculi. However, F-URS is an alternative technique in selected patients with a patent infundibulum, despite lower stone-free rates than with MPCNL. Fulguration of the diverticular lining with a high-power holmium laser and permitting the cavity to collapse are useful to increase the chance of diverticular obliteration. |
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Bibliography: | Caliceal diverticular calculi;Minimally invasive percutaneous nephrolithotomy;Flexible ureterorenoscopy Objective: To retrospectively evaluate appropriate treatment for patients with symptomatic caliceal diverticular calculi, by comparing the therapeutic outcomes for those undergoing minimally invasive percutaneous nephrolithotomy (MPCNL) and flexible ureterorenoscopy (F-URS). Methods: From March 2009 to May 2014, 36 consecutive patients with caliceal diverticular calculi were divided into 2 groups:21 patients underwent MPCNL, and 15 were treated by F-URS. All procedures were performed by one surgical group, which ensured relatively constant parameters. Patient characteristics, operative time, hospital stay after surgery, stone-free rate, symptomatic improvement rate, complications, diverticular obliteration, and stone composition were analyzed retrospectively in the 2 groups. Results: Patient preoperative variables were comparable between the two groups, with no significant difference (P>0.05). Mean operative time was 136.9 ± 22.8 min in the MPCNL group and 117.3 ± 24.3 min in the F-URS group (P ? 0.019). Hospital stay was significantly longer in the MPCNL group than in the F-URS group (9.4 ± 3.1 vs. 6.9 ± 2.1 days, P ? 0.010). The stone-free rates after MPCNL and F-URS were 90.5%(19/21) and 60.0%(9/15), respectively (P ? 0.046). Additionally, 71.4%(15/21) of patients in the MPCNL group and 46.7%(7/15) of patients in the F-URS group had symptomatic improvement at the 6-month follow-up (P ? 0.175);the rates of complications in the 2 groups were 19.0%(4/21) and 13.3%(2/15), respectively (P ? 0.650). Complete diverticular obliteration was achieved in 16 (76.2%) cases in the MPCNL group and 5 (33.3%) cases in the F-URS group (P ? 0.017). The distributions of calcium oxalate and hydroxyapatite in the stones were 66.7% (14/21) and 33.3% (7/21), respectively, in the MPCNL group;however, the distributions in the F-URS group were 46.7%(7/15) and 53.3%(8/15), respec-tively (P ? 0.310). Conclusion: MPCNL is an effective method for the treatment of caliceal diverticular calculi. However, F-URS is an alternative technique in selected patients with a patent infundibulum, despite lower stone-free rates than with MPCNL. Fulguration of the diverticular lining with a high-power holmium laser and permitting the cavity to collapse are useful to increase the chance of diverticular obliteration. Xiang Ding[1];Song-Tao Xu[2];Yu-Hua Huang[1];Xue-Dong Wei[1];Jiang-Lei Zhang[1];Liang-Liang Wang[1];Jin-Xian Pu[1];Jian-Quan Hou[1];Chun-Yin Yan[1];Feng-Mei Cui[3] 10-1249/R The three authors contribute equally to the work. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 2095-882X 2589-0514 2589-0514 |
DOI: | 10.1016/j.cdtm.2016.11.016 |