伴发库欣综合征血糖控制不佳的糖尿病一例并文献复习

报道1例血糖控制不佳伴发库欣综合征的糖尿病患者，以提醒临床注意。患者52岁，女性，诊断为2型糖尿病6年，经较为规范地生活方式干预及胰岛素等药物治疗，血糖控制不佳。为寻求高血糖原因第5次入院时，发现垂体促肾上腺皮质激素瘤，经鼻蝶窦入路垂体腺瘤切除术后血糖大为改善。病例提示对于血糖控制不佳的2型糖尿病患者，尤其是伴有圆脸、高血压、血脂紊乱及中心性肥胖者，应警惕伴发库欣综合征的可能。...

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Bibliographic Details
Published in中华糖尿病杂志 Vol. 9; no. 2; pp. 130 - 133
Main Author 裴育 金楠 李楠 卢艳慧 李剑 巴建明 窦京涛
Format Journal Article
LanguageChinese
Published 解放军总医院内分泌科, 北京,100853%解放军总医院老年内分泌科, 北京,100853 2017
Subjects
2型
库欣综合征
糖尿病
血糖控制
Glycemic control
type 2
血糖控制
库欣综合征
Diabetes mellitus
糖尿病,2型
Cushing's syndrome
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Summary:报道1例血糖控制不佳伴发库欣综合征的糖尿病患者，以提醒临床注意。患者52岁，女性，诊断为2型糖尿病6年，经较为规范地生活方式干预及胰岛素等药物治疗，血糖控制不佳。为寻求高血糖原因第5次入院时，发现垂体促肾上腺皮质激素瘤，经鼻蝶窦入路垂体腺瘤切除术后血糖大为改善。病例提示对于血糖控制不佳的2型糖尿病患者，尤其是伴有圆脸、高血压、血脂紊乱及中心性肥胖者，应警惕伴发库欣综合征的可能。
Bibliography:Pei Yu, Jin Nan, Li Nan, Lu Yanhui, Li Jian, Ba Jianming, Dou Jingtao（ Department of Endocrinology, Chinese PLA General Hospital, Belting 100853, China）
Diabetes mellitus, type 2; Cushing＇s syndrome; Glyceraic control
A case of type 2 diabetes mellitus（T2DM） with poor glycemic control combined with Cushing＇s syndrome was reported to remind clinicians＇ attention. A 52-year-old female has been diagnosed as T2DM for 6 years. Her blood glucose was controlled poorly with insulin therapy and appropriate life style intervention. On the fifth time of admission, this patient was diagnosed as pituitary adrenocorticotropic hormone secreting adenoma. The blood glucose was well-controlled after transsphenoidal pituitary adenoma resection. It indicates that examination for hypercortisolism should be performed in T2DM patients with poor glycemic control, especially in those with a round face, hypertension, dyslipidemia or truncal obesity.
11-5791/R
ISSN:1674-5809
DOI:10.3760/cma.j.issn.1674?5809.2017.02.010