Development and characterization of magnetic molecularly imprinted polymers for the selective enrichment of endocrine disrupting chemicals in water and milk samples

• Published in: Analytical and bioanalytical chemistry Vol. 407; no. 6; pp. 1735 - 1744
• Main Authors: Xie, Xiaoyu, Pan, Xiaoyan, Han, Shengli, Wang, Sicen
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2015; Springer; Springer Nature B.V
• Subjects: Adsorption; Analytical Chemistry; Animals; Binding sites; Biochemistry; Biopolymers; Bisphenol A; Cancer; Characterization and Evaluation of Materials; Chemical properties; Chemistry; Chemistry and Materials Science; Composition; Disrupting; Endocrine disruptors; Endocrine Disruptors - analysis; Enrichment; Estrogens; Food Science; Fourier transforms; Identification and classification; Imprinted polymers; Isotherms; Laboratory Medicine; Liquid chromatography; Magnetic properties; Magnetics; Mathematical analysis; Medical equipment; Milk; Milk - chemistry; Molecular Imprinting; Monitoring/Environmental Analysis; Nanoparticles; Nanostructure; Polymers; Polymers - chemistry; Production processes; Research Paper; Surface chemistry; Water Pollutants, Chemical - analysis; X-ray diffraction; United States > US; China; Japan; Germany; Molecularly imprinted polymers; Super paramagnetic; Water and milk; Endocrine disrupting chemicals
• ISSN: 1618-2642; 1618-2650
• DOI: 10.1007/s00216-014-8425-0

Analyses of four endocrine disrupting chemicals (EDCs) in water and milk samples were undertaken by using magnetic molecularly imprinted polymers (MMIPs). These were prepared via the surface molecular imprinting technique using super paramagnetic core-shell nanoparticle as support. Diethylstilbestrol (DES), which is a typical EDC, was employed as the template molecule. The obtained MMIPs were characterized using transmission electron microscope, Fourier transform infrared, X-ray diffraction, and vibrating sample magnetometer. Accordingly, the adsorption capacity and selectivity of prepared MMIPs were investigated. The binding isotherms were obtained for DES and fitted by the Freundlich isotherm model. A corresponding analytical method to determine four EDCs was developed. The recoveries of the spiked samples in pond water and pure milk range from 67.8 to 93.2 % and from 65.3 to 92.5 %, respectively. Coupled with high-performance liquid chromatography analysis, the prepared MMIPs were successfully applied to the analysis of EDCs in water and milk samples. Graphical Abstract The construction and feature of magnetic molecularly imprinted polymers