Critical evaluation of biodegradable polymers used in nanodrugs

Use of biodegradable polymers for biomedical applications has increased in recent decades due to their biocompatibility, biodegradability, flexibility, and minimal side effects. Applications of these materials include creation of skin, blood vessels, cartilage scaffolds, and nanosystems for drug del...

Full description

Saved in:
Bibliographic Details
Published inInternational Journal of Nanomedicine Vol. 8; no. 1; pp. 3071 - 3091
Main Authors Marin, Edgar, Briceño, Maria Isabel, Caballero-George, Catherina
Format Journal Article Book Review
LanguageEnglish
Published New Zealand Dove Medical Press Limited 01.01.2013
Taylor & Francis Ltd
Dove Press
Dove Medical Press
Subjects
Animals
Biocompatible Materials
Biodegradable materials
biodegradable polymers
biomedical applications
Biopolymers
Cell Line
cellular uptake
Drug Carriers
drug delivery
Drug delivery systems
Drugs
Endocytosis
Humans
Mice
Nanomedicine
Nanoparticles
Polymers
Properties
Review
Vehicles
India
nanoparticles
drug delivery
biodegradable polymers
biomedical applications
cellular uptake
Online AccessGet full text

Cover

More Information
Summary:Use of biodegradable polymers for biomedical applications has increased in recent decades due to their biocompatibility, biodegradability, flexibility, and minimal side effects. Applications of these materials include creation of skin, blood vessels, cartilage scaffolds, and nanosystems for drug delivery. These biodegradable polymeric nanoparticles enhance properties such as bioavailability and stability, and provide controlled release of bioactive compounds. This review evaluates the classification, synthesis, degradation mechanisms, and biological applications of the biodegradable polymers currently being studied as drug delivery carriers. In addition, the use of nanosystems to solve current drug delivery problems are reviewed.
ISSN:1178-2013
1176-9114
1178-2013
DOI:10.2147/IJN.S47186