Identification of alcaligin as the siderophore produced by Bordetella pertussis and B. bronchiseptica

The siderophores produced by iron-starved Bordetella pertussis and B. bronchiseptica were purified and were found to be identical. Using mass spectrometry and proton nuclear magnetic resonance, we determined that the siderophore produced by these organisms was identical to alcaligin, a siderophore p...

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Published inJournal of Bacteriology Vol. 177; no. 4; pp. 1116 - 1118
Main Authors Moore, C.H. (Massey University, Palmerston North, New Zealand), Foster, L.A, Gerbig, D.G. Jr, Dyer, D.W, Gibson, B.W
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 01.02.1995
Subjects
Alcaligenes - chemistry
Alcaligenes denitrificans
Bacteriology
BORDETELLA
BORDETELLA BRONCHISEPTICA
Bordetella bronchiseptica - chemistry
Bordetella pertussis
Bordetella pertussis - chemistry
Chromatography, High Pressure Liquid
Dose-Response Relationship, Drug
Hydroxamic Acids
Iron
Iron - metabolism
Mass Spectrometry
Medical research
Respiratory diseases
SIDEROFOROS
SIDEROPHORE
Siderophores - chemistry
Siderophores - isolation & purification
Siderophores - pharmacology
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Summary:The siderophores produced by iron-starved Bordetella pertussis and B. bronchiseptica were purified and were found to be identical. Using mass spectrometry and proton nuclear magnetic resonance, we determined that the siderophore produced by these organisms was identical to alcaligin, a siderophore produced by Alcaligenes denitrificans
Bibliography:L73
9539189
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ISSN:0021-9193
1098-5530
1067-8832
DOI:10.1128/jb.177.4.1116-1118.1995