Nutritional Supplements in Support of Resistance Exercise to Counter Age-Related Sarcopenia

Age-related sarcopenia, composed of myopenia (a decline in muscle mass) and dynapenia (a decline in muscle strength), can compromise physical function, increase risk of disability, and lower quality of life in older adults. There are no available pharmaceutical treatments for this condition, but evi...

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Bibliographic Details
Published inAdvances in food and nutrition research Vol. 6; no. 4; pp. 452 - 460
Main Author Phillips, Stuart M
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.07.2015
American Society for Nutrition
Subjects
adverse effects
Aged
Aging
creatine
Creatine - administration & dosage
Diet
Dietary Proteins - administration & dosage
Dietary Supplements
dynapenia
elderly
Fatty Acids, Omega-3 - administration & dosage
Female
foods
function
Humans
Leu
Leucine - administration & dosage
Male
Muscle Strength
Muscle, Skeletal - pathology
Muscle, Skeletal - physiopathology
muscles
nutrients
protein
Quality of Life
Resistance Training
Reviews
risk
sarcopenia
Sarcopenia - therapy
strength training
Valerates - administration & dosage
vitamin D
β-HMB
1-RM
RT
EAA
PDCAAS
vitamin D
β-HMB
p70S6k1
DIAAS
4EBP1
MPS
creatine
function
protein
mTOR
aging
Leu
mTORC1
MPB
dynapenia
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Summary:Age-related sarcopenia, composed of myopenia (a decline in muscle mass) and dynapenia (a decline in muscle strength), can compromise physical function, increase risk of disability, and lower quality of life in older adults. There are no available pharmaceutical treatments for this condition, but evidence shows resistance training (RT) is a viable and relatively low-cost treatment with an exceptionally positive side effect profile. Further evidence suggests that RT-induced increases in muscle mass, strength, and function can be enhanced by certain foods, nutrients, or nutritional supplements. This brief review focuses on adjunctive nutritional strategies, which have a reasonable evidence base, to enhance RT-induced gains in outcomes relevant to sarcopenia and to reducing risk of functional declines.
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The author reported no funding received for this study.
Author disclosures: SM Phillips has received research grant funding from The Canadian Institutes for Health Research (MOP 123296) and The National Science and Engineering Research Council, Dairy Farmers of Canada, and the US Dairy Research Institute; has undertaken contract research sponsored by Nestlé has provided consultation and has spoken on behalf of the Dairy Farmers of Canada, the US National Dairy Council, Nestlé, and the US National Cattlemen’s Beef Association; and for these services has received cost of living, travel expenses, and, on occasion, honoraria.
ISSN:2161-8313
2156-5376
1043-4526
2156-5376
DOI:10.3945/an.115.008367