Patient-specific computational modeling of blood flow in the pulmonary arterial circulation

Highlights • We applied computational fluid dynamics modeling to 11 pulmonary vascular trees. • Patient-specific cardiac output is necessary to obtain accurate wall shear stress. • Spatially averaged wall shear stress is highly correlated with pulmonary vascular resistance. • Spatially averaged wall...

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Bibliographic Details
Published inComputer methods and programs in biomedicine Vol. 120; no. 2; pp. 88 - 101
Main Authors Kheyfets, Vitaly O, Rios, Lourdes, Smith, Triston, Schroeder, Theodore, Mueller, Jeffrey, Murali, Srinivas, Lasorda, David, Zikos, Anthony, Spotti, Jennifer, Reilly, John J, Finol, Ender A
Format Journal Article
LanguageEnglish
Published Ireland Elsevier Ireland Ltd 01.07.2015
Subjects
Boundary conditions
Cohort Studies
Computational fluid dynamics
Computer Simulation
Disease Progression
Hemodynamics
Humans
Internal Medicine
Other
Patients
Pulmonary Artery - physiology
Pulmonary hypertension
Pulmonary vascular resistance
Regional Blood Flow
Vessel diameter
Boundary conditions
Vessel diameter
Hemodynamics
Computational fluid dynamics
Pulmonary vascular resistance
Pulmonary hypertension
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Summary:Highlights • We applied computational fluid dynamics modeling to 11 pulmonary vascular trees. • Patient-specific cardiac output is necessary to obtain accurate wall shear stress. • Spatially averaged wall shear stress is highly correlated with pulmonary vascular resistance. • Spatially averaged wall shear stress is highly correlated with arterial compliance. • Structured-tree outflow boundary conditions improve these correlations.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0169-2607
1872-7565
DOI:10.1016/j.cmpb.2015.04.005