ROLE of exercise in maintaining the integrity of the neuromuscular junction

• Published in: Muscle & nerve Vol. 49; no. 3; pp. 315 - 324
• Main Authors: Nishimune, Hiroshi, Stanford, John A., Mori, Yasuo
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.03.2014; Wiley Subscription Services, Inc
• Subjects: active zone; aging; Aging - physiology; Animals; Exercise; Exercise - physiology; Humans; laminin; Muscular system; Nerve Tissue Proteins - metabolism; Neuregulin-1 - metabolism; Neuromuscular Junction - metabolism; Neuromuscular Junction - physiology; Physical fitness; PPAR gamma - metabolism; synapse; exercise; laminin; aging; synapse; active zone

ABSTRACT Physical activity plays an important role in preventing chronic disease in adults and the elderly. Exercise has beneficial effects on the nervous system, including at the neuromuscular junction (NMJ). Exercise causes hypertrophy of NMJs and improves recovery from peripheral nerve injuries,...