40岁以上人群肱踝脉搏波传导速度与心脑血管事件关系的前瞻性研究

目的探讨40岁以上人群肱踝脉搏波传导速度（ba-PWV）与心脑血管事件发生风险的关系。方法2011年5月—8月，采用整群抽样法对贵阳市云岩区4380例40岁以上常住居民进行前瞻性研究，检测该人群的ba-PWV并收集基线资料，剔除不符合条件及患心脑血管疾病者，将4189例无心脑血管疾病的人群作为本研究的基线样本，于2014年7月—11月对该人群进行随访。根据ba-PWV值将将最终完成随访的3241例分为3组：＜14m/s组（正常组，1039例）、14～17.9m/s组（1393例）、≥18m/s组（809例）。应用多因素Logistic回归模型分析ba-PWV与心脑血管事件发生风险的关系。结果3...

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Bibliographic Details
Published in天津医药 Vol. 44; no. 8; pp. 963 - 966
Main Author 赵胜仙;彭年春;时立新;张巧;胡颖;徐淑静;张淼;张松
Format Journal Article
LanguageChinese
Published 贵州医科大学附属医院内分泌代谢病科 邮编550004 2016
Subjects
脉搏;心血管系统;前瞻性研究;随访研究;肱踝脉搏波传导速度;心脑血管事件
cardio-cerebral events
前瞻性研究
cardiovascular system
follow-up studies
brachial ankle pulse wave velocity
脉搏
prospective studies
pulse
心血管系统
肱踝脉搏波传导速度
随访研究
心脑血管事件
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Summary:目的探讨40岁以上人群肱踝脉搏波传导速度（ba-PWV）与心脑血管事件发生风险的关系。方法2011年5月—8月，采用整群抽样法对贵阳市云岩区4380例40岁以上常住居民进行前瞻性研究，检测该人群的ba-PWV并收集基线资料，剔除不符合条件及患心脑血管疾病者，将4189例无心脑血管疾病的人群作为本研究的基线样本，于2014年7月—11月对该人群进行随访。根据ba-PWV值将将最终完成随访的3241例分为3组：＜14m/s组（正常组，1039例）、14～17.9m/s组（1393例）、≥18m/s组（809例）。应用多因素Logistic回归模型分析ba-PWV与心脑血管事件发生风险的关系。结果3年后发生心脑血管事件共63例（2.0%），正常组、14～17.9m/s组、≥18m/s组心脑血管事件发生率分别为0.6%、2.2%、3.2%，ba-PWV升高的两组均高于正常组，差异有统计学意义。Logistic回归分析显示，调整年龄、性别、收缩压、糖尿病、高血压、血脂异常等危险因素后，14～17.9m/s组、≥18m/s组发生心脑血管事件风险比是正常组的2.777（1.123～6.864）倍、2.786（1.032～7.526）倍。结论40岁以上人群中，ba-PWV升高组心脑血管事件发生率较高，ba-PWV可以预测心脑血管事件的发生风险。
Bibliography:Objective To investigate the relationship between brachial ankle pulse wave velocity and the incidence of cardio-cerebral events in people aged over 40. Methods Cluster sampling method was used to prospectively study 4 380 residents aged over 40 in Guiyang City District from May to August in 2011. Data of ba-PWV were collected. The follow-up examination was conducted from July to November of 2014. According to ba-PWV values, participants were divided into three groups: <14 m/s (control, n=1 039) group, 14-17.9 m/s group (n=1 393) and ≥18 m/s group (n=809). Multi-factor Logistic regression model was used to analyze the relationship between ba-PWV values and risk factors of cardio-cerebral events.Results After three-year follow-up, a total of 3 241 participants were included in the final analysis. The cardio-cerebral events were identified in 63 (2.0%) cases, which were 0.6%, 2.2% and 3.2% in control group, 14-17.9 m/s group and ≥18 m/s group.The value of ba-PWV increased significantly in those two groups co
ISSN:0253-9896
DOI:10.11958/20160079