Cross Reactivity of Schistosome Antigens between Schistosoma mansoni and japonicum

Fifty six patients with chronic Schistosomiasis japonica were given skin tests with preparations made of Schistosora mansoni and Schistosoma japonicum. There was a high, significant positive correlation between the results of both antigens. Among 47 serum samples tested with indirect hemagglutinatio...

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Published inThe Tohoku Journal of Experimental Medicine Vol. 127; no. 2; pp. 151 - 156
Main Authors KITANI, KENICHI, MIURA, REIKO, IUCHI, MASAHIKO
Format Journal Article
LanguageEnglish
Published Japan Tohoku University Medical Press 01.01.1979
Subjects
Antigens - immunology
Chronic Disease
Cross Reactions
cross reactivity
Female
Hemagglutination Tests
Humans
Male
Schistosoma japonicum
Schistosoma japonicum - immunology
Schistosoma mansoni
Schistosoma mansoni - immunology
Schistosomiasis - immunology
schistosomiasis japonica
Skin Tests
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Summary:Fifty six patients with chronic Schistosomiasis japonica were given skin tests with preparations made of Schistosora mansoni and Schistosoma japonicum. There was a high, significant positive correlation between the results of both antigens. Among 47 serum samples tested with indirect hemagglutination (IHA) 27 had the antibody titer 1:16 or higher, which was diagnostically significant in combination with positive skin test results. The results indicate a definite cross reactivity of japonicum and mansoni anitgens in patients with Schistosomiasis japonica.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0040-8727
1349-3329
DOI:10.1620/tjem.127.151