Different phenotypes of polycystic ovary syndrome by Rotterdam criteria are differently steroidogenic but similarly insulin resistant

In traditional Chinese medicine, polycystic ovary syndrome (PCOS) is considered an anovulation disorder related to ovarian insulin resistance. The three phenotypes of PCOS, according to the Rotterdam criteria, are differently steroidogenic but similarly insulin resistant, suggesting a similar involv...

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Bibliographic Details
Published inFertility and sterility Vol. 93; no. 4; pp. 1362 - 1365
Main Authors Wang, Yong, Ph.D, Qu, JunWei, M.D, Wu, XiaoKe, M.D., Ph.D, Hou, LiHui, M.D, Erkkola, Risto, M.D., Ph.D, Wang, Yongyan, M.D
Format Journal Article Conference Proceeding
LanguageEnglish
Published New York, NY Elsevier Inc 01.03.2010
Elsevier
Subjects
Adult
Biological and medical sciences
Diagnostic Tests, Routine - standards
Female
Female genital diseases
Gynecology. Andrology. Obstetrics
Humans
Insulin Resistance - genetics
Internal Medicine
Medical sciences
Non tumoral diseases
Obstetrics and Gynecology
Ovary - pathology
Phenotype
Pilot Projects
Polycystic Ovary Syndrome - classification
Polycystic Ovary Syndrome - diagnosis
Polycystic Ovary Syndrome - genetics
Ovarian diseases
Phenotype
Gynecology
Cyst
Female sterility
Benign neoplasm
Polycystic ovary
Insulin
Obstetrics
Female genital diseases
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Summary:In traditional Chinese medicine, polycystic ovary syndrome (PCOS) is considered an anovulation disorder related to ovarian insulin resistance. The three phenotypes of PCOS, according to the Rotterdam criteria, are differently steroidogenic but similarly insulin resistant, suggesting a similar involvement of insulin resistance/hyperinsulinemia in different compartments of the PCOS ovary, namely, overactive theca and/or granulosa cells.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0015-0282
1556-5653
DOI:10.1016/j.fertnstert.2009.07.1678