SARS-CoV-2 Omicron Variant Neutralization after mRNA-1273 Booster Vaccination
Neutralization of the omicron variant was assessed in serum samples obtained from persons who had received an mRNA-1273 booster. After the standard two-dose vaccine regimen, these titers were approximately 35 times lower than those against the D614G variant. However, boosters increased omicron neutr...
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Published in | New England Journal of Medicine Vol. 386; no. 11; pp. 1088 - 1091 |
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Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Format | Journal Article Web Resource |
Language | English |
Published |
United States
Massachusetts Medical Society
17.03.2022
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Subjects | |
Online Access | Get full text |
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Summary: | Neutralization of the omicron variant was assessed in serum samples obtained from persons who had received an mRNA-1273 booster. After the standard two-dose vaccine regimen, these titers were approximately 35 times lower than those against the D614G variant. However, boosters increased omicron neutralization by a factor of 20 — to levels that correlate with clinical resistance to infection. |
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Bibliography: | SourceType-Other Sources-1 ObjectType-Article-1 content type line 63 ObjectType-Correspondence-2 |
ISSN: | 0028-4793 1533-4406 |
DOI: | 10.1056/NEJMc2119912 |