Effect of immobilization stress on testosterone and inhibin in male rats

• Published in: Journal of andrology Vol. 10; no. 3; pp. 210 - 213
• Main Authors: Demura, R, Suzuki, T, Nakamura, S, Komatsu, H, Odagiri, E, Demura, H
• Format: Journal Article
• Language: English
• Published: Oxford, UK Am Soc Andrology 01.05.1989; Blackwell Publishing Ltd; American Society of Andrology
• Subjects: Animals; Biological and medical sciences; Follicle Stimulating Hormone - blood; FSH; Fundamental and applied biological sciences. Psychology; GnRH; Hormone metabolism and regulation; Immobilization stress; inhibin; Inhibins - analysis; Luteinizing Hormone - blood; Male; Mammalian male genital system; Rats; Rats, Inbred Strains; Restraint, Physical; Space life sciences; Stress, Physiological - blood; Stress, Physiological - metabolism; Testis - analysis; testosterone; Testosterone - analysis; Testosterone - blood; Vertebrates: reproduction; Testosterone; Vertebrata; Restraint stress; Mammalia; Rat; Rodentia; Peptide hormone; Inhibin; Gonadotropin; Testicular hormone; Sex steroid hormone
• ISSN: 0196-3635; 1939-4640
• DOI: 10.1002/j.1939-4640.1989.tb00089.x

Adult male Wistar rats were subjected to acute and chronic immobilization stress. Changes in plasma levels of LH, FSH and testosterone and in the content of testicular inhibin and testosterone were studied. Plasma LH levels decreased significantly in response to both acute and chronic stress. Significant decreases in plasma testosterone content were also observed after chronic stress. In contrast, plasma FSH and testicular bioassayable inhibin content did not change after acute or chronic stress. These findings indicate that in male rats immobilization stress induced a dissociation in LH and FSH responses, and decreased testosterone while inhibin remained unaffected.