Prevention and control of HIV/AIDS in China: lessons from the past three decades

• Published in: Chinese medical journal Vol. 134; no. 23; pp. 2799 - 2809
• Main Authors: Xu, Jun-Jie, Han, Meng-Jie, Jiang, Yong-Jun, Ding, Hai-Bo, Li, Xi, Han, Xiao-Xu, Lv, Fan, Chen, Qing-Feng, Zhang, Zi-Ning, Cui, Hua-Lu, Geng, Wen-Qing, Zhang, Jing, Wang, Qi, Kang, Jing, Li, Xiao-Lin, Sun, Hong, Fu, Ya-Jing, An, Ming-Hui, Hu, Qing-Hai, Chu, Zhen-Xing, Liu, Ying-Jie, Shang, Hong
• Format: Journal Article
• Language: English
• Published: China Lippincott Williams & Wilkins 05.12.2021; Lippincott Williams & Wilkins Ovid Technologies; NHC Key Laboratory of AIDS Immunology (China Medical University), National Clinical Research Center for Laboratory Medicine, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China%Key Laboratory of AIDS Immunology of Liaoning Province, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China%Key Laboratory of AIDS Immunology, Chinese Academy of Medical Sciences, Shenyang, Liaoning 110001, China%Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, Zhejiang 310003, China%National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China%National Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China; Wolters Kluwer
• Subjects: Acquired immune deficiency syndrome; Acquired Immunodeficiency Syndrome - drug therapy; Acquired Immunodeficiency Syndrome - epidemiology; Acquired Immunodeficiency Syndrome - prevention & control; AIDS; Antiretroviral drugs; China - epidemiology; Disease Outbreaks; Disease prevention; HIV; HIV Infections - drug therapy; HIV Infections - epidemiology; HIV Infections - prevention & control; Human immunodeficiency virus; Humans; Mortality; Prevalence; Review; China; United States > US; Human immunodeficiency virus; Transmission route; Antiretroviral therapy; Acquired immunodeficiency syndrome; HIV-1 subtype
• ISSN: 0366-6999; 2542-5641; 2542-5641
• DOI: 10.1097/CM9.0000000000001842

In the past 37 years, human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) has undergone various major transmission routes in China, with the world most complex co-circulating HIV-1 subtypes, even the prevalence is still low. In response to the first epidemic outbreak of HIV in injecting drug users and the second one by illegal commercial blood collection, China issued the Anti-Drug Law and launched the Blood Donation Act and nationwide nucleic acid testing, which has avoided 98,232 to 211,200 estimated infections and almost ended the blood product-related infection. China has been providing free antiretroviral therapy (ART) since 2003, which covered >80% of the identified patients and achieved a viral suppression rate of 91%. To bend the curve of increasing the disease burden of HIV and finally end the epidemic, China should consider constraining HIV spread through sexual transmission, narrowing the gaps in identifying HIV cases, and the long-term effectiveness and safety of ART in the future.