Neuromuscular fatigue development during maximal concentric and isometric knee extensions

• Published in: Journal of applied physiology (1985) Vol. 100; no. 3; pp. 780 - 785
• Main Authors: Babault, Nicolas, Desbrosses, Kevin, Fabre, Marie-Sophie, Michaut, Anne, Pousson, Michel
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Am Physiological Soc 01.03.2006; American Physiological Society
• Subjects: Adult; Biological and medical sciences; Biomechanical Phenomena; Data Interpretation, Statistical; Electric Stimulation; Electromyography; Exercise - physiology; Fatigue; Fundamental and applied biological sciences. Psychology; Human health and pathology; Humans; Isometric Contraction - physiology; Knee; Knee Joint - physiology; Life Sciences; Male; Muscle Contraction; Muscle Fatigue - physiology; Muscle, Skeletal - innervation; Muscle, Skeletal - physiology; Muscle, Skeletal - physiopathology; Muscular system; Nervous system; Neuromuscular Junction - physiology; Physical Endurance - physiology; Pliability; Time Factors; Tissues and Organs; Torque; Extension; Knee; Vertebrata; Mammalia; twitch interpolation; Electrophysiology; Development; Fatigue; Electromyography; evoked contractions; Muscle contraction
• ISSN: 8750-7587; 1522-1601
• DOI: 10.1152/japplphysiol.00737.2005

1 Performance Motrice et Santé, Unité de Formation et de Recherche des Sciences et Techniques des Activités Physiques et Sportives, Université Marc Bloch, Strasbourg Cedex; 2 Institut National de la Santé et de la Recherche Médicale/Equipe de Recherche et d'Innovation Technologique-M 0207 Motricité-Plasticité, Faculté des Sciences du Sport, Université de Bourgogne, Dijon Cedex; 3 Institut National de Recherche et de Sécurité, Laboratoire de Physiologie du Travail, Vandoeuvre Cedex; and 4 Laboratoire de Biomécanique et de Physiologie, Institut National du Sport et de l'Education Physique, Paris, France Submitted 22 June 2005 ; accepted in final form 7 November 2005 This study aimed to investigate mechanisms of neuromuscular fatigue during maximal concentric and isometric leg extensions inducing similar torque decrements. Nine physically active men performed two separate fatiguing sessions maintained until similar torque decreases were obtained. The first session, only conducted under isokinetic concentric conditions (CON), consisted of three series of 30 maximal voluntary concentric knee extensions (60°/s). The second session, exclusively isometric (ISO), mimicked the torque decreases registered during the CON session while performing three long-lasting ISO contractions. Maximal voluntary torque, activation level (twitch interpolation technique), electromyographic activity (root mean square and median frequency) of the vastus lateralis muscle, and electrically evoked doublet-twitch mechanical properties were measured before and at the end of each of the three series. After the three series, similar torque decrements were obtained for both fatiguing procedures. The total fatiguing contraction durations were not different among procedures. With equivalent voluntary torque decrements, the doublet-twitch amplitude reduction was significantly greater ( P < 0.01) during the two first series of the CON procedure compared with ISO. No difference was observed for the third series. Although no difference was recorded with fatigue for median frequency changes between CON and ISO, activation levels and root mean square values demonstrated greater reductions ( P < 0.05) for all three series during the ISO procedure compared with CON. Performing CON or ISO fatiguing exercises demonstrated different fatigue origins. With CON exercises, peripheral fatigue developed first, followed by central fatigue, whereas with ISO exercises the fatigue pattern was inverted. electromyography; evoked contractions; twitch interpolation Address for reprint requests and other correspondence: N. Babault, UFR STAPS, Université Marc Bloch, 14 rue René Descartes, 67084 Strasbourg Cedex, France (e-mail: nbabault{at}umb.u-strasbg.fr )