Erythrocyte sedimentation rate and red blood cell indices association in pediatrics patients with fever and cough: A cross‐sectional study

• Published in: Health science reports Vol. 7; no. 1; pp. e1843 - n/a
• Main Authors: Pourfridoni, Mohammad, Farhadi Rad, Hamidreza, Mirzaee, Faezeh, Abbasnia, Seyede Mahsa, Nikvarz, Mehran, Sharifi, Elham, Shafiei, Shohreh, Baghcheghi, Yousef, Amiri Domari, Asma, Askarpour, Hedyeh
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.01.2024; John Wiley and Sons Inc; Wiley
• Subjects: Biomarkers; Blood tests; cough; Cross-sectional studies; Data analysis; Disease; erythrocyte sedimentation rate; Fever; Gender; Hemoglobin; Hospitalization; Inflammation; Normal distribution; Original Research; Patients; Pediatrics; red blood cell indices; Variables; erythrocyte sedimentation rate; fever; red blood cell indices; cough; pediatrics
• ISSN: 2398-8835; 2398-8835
• DOI: 10.1002/hsr2.1843

Background and Aims The erythrocyte sedimentation rate (ESR) is an essential inflammatory marker in treating some patients, particularly children. The level of ESR can be affected by red blood cell (RBC) indices, and not considering this can complicate the interpretation of ESR and the treatment and follow‐up of patients. The study aimed to assess the association between ESR and RBC indices in children hospitalized with fever and cough in the pediatric ward of Imam Khomeini Hospital, Jiroft, in 2023. Methods A cross‐sectional study was conducted to measure the association between ESR and RBC indices in children hospitalized with fever and cough in the pediatric ward of Imam Khomeini Hospital, Jiroft, in 2023. A total of 156 patients participated in the study. SPSS software was used for statistical analysis. Results The mean age of participants was 27.26 ± 3.14 months. The results showed that there is a significant negative correlation between ESR and RBC, r = −0.282 (p < 0.001), and ESR and hematocrit (HCT), r = −0.215 (p = 0.007). Also, the results demonstrated that there is a significant positive correlation between ESR and mean corpuscular volume (MCV), r = 0.159 (p = 0.048), ESR and mean corpuscular hemoglobin (MCH), r = 0.214 (p = 0.007), and ESR and mean cell hemoglobin concentration (MCHC), r = 0.209 (p = 0.009). There was a negative correlation between ESR and hemoglobin (Hb), r = −0.98 (p = 0.225), but this correlation was insignificant. Conclusion This study showed an association between ESR and RBC indices in hospitalized children with complaints of fever and cough. So, it is necessary that physicians and treatment staff pay attention to the RBC indices while interpreting and following up the results of ESR to complete the treatment process of patients.