The effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in Singapore

Hidradenitis suppurativa (HS) is a chronic inflammatory disease of follicular occlusion characterized by abscesses, draining sinuses, and scarring. The efficacy and tolerability of combination treatment with oral clindamycin and rifampicin have previously been assessed in 4 studies including groups...

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Published inClinical, cosmetic and investigational dermatology Vol. 11; pp. 37 - 39
Main Authors Ochi, Harumi, Tan, Lixian Chris, Oon, Hazel H
Format Journal Article
LanguageEnglish
Published New Zealand Dove Medical Press Limited 01.01.2018
Taylor & Francis Ltd
Dove Medical Press
Subjects
Abscess
Antibacterial agents
Care and treatment
Clindamycin
combination therapy
Communicable diseases
Complications and side effects
hidradenitis suppurativa
Medical research
Pathogenic microorganisms
Research Letter
rifampicin
Rifampin
Staphylococcus aureus
Staphylococcus aureus infections
rifampicin
combination therapy
hidradenitis suppurativa
clindamycin
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Summary:Hidradenitis suppurativa (HS) is a chronic inflammatory disease of follicular occlusion characterized by abscesses, draining sinuses, and scarring. The efficacy and tolerability of combination treatment with oral clindamycin and rifampicin have previously been assessed in 4 studies including groups of Caucasian patients. Overall results are promising with reported improvement rates between 71.4% and 85.7%. In this study, we propose that combination therapy is safe and efficacious in the treatment of HS, not only among Caucasians, but also in a group of Asian patients in Singapore.
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ISSN:1178-7015
1178-7015
DOI:10.2147/CCID.S136730