Genome Size and Structure Determine Efficiency of Postinternalization Steps and Gene Transfer of Capsid-Modified Adenovirus Vectors in a Cell-Type-Specific Manner

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Published inJournal of Virology Vol. 78; no. 18; pp. 10009 - 10022
Main Authors SHAYAKHMETOV, Dmitry M, LI, Zong-Yi, GAGGAR, Anuj, GHARWAN, Helen, TERNOVOI, Vladimir, SANDIG, Volker, LIEBER, André
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.09.2004
Subjects
Active Transport, Cell Nucleus
Adenoviruses, Human - classification
Adenoviruses, Human - genetics
Adenoviruses, Human - physiology
Biological and medical sciences
Capsid Proteins - genetics
Capsid Proteins - physiology
Cell Line
DNA, Viral - genetics
DNA, Viral - metabolism
Endosomes - virology
Fundamental and applied biological sciences. Psychology
Gene Therapy
Gene Transfer Techniques
Genetic Vectors
Genetics
Genome, Viral
Green Fluorescent Proteins
Human adenovirus 5
Humans
Luminescent Proteins - genetics
Luminescent Proteins - metabolism
Microbiology
Microscopy, Electron
Miscellaneous
Recombinant Proteins - genetics
Recombinant Proteins - metabolism
Virology
Virus
Adenoviridae
Gene
Microbiology
Efficiency
Size
Capsid
Genome
Vector
Genetic transfer
Virology
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Summary:Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue JVI About JVI Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy JVI RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0022-538X Online ISSN: 1098-5514 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to JVI .asm.org, visit: JVI       
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Corresponding author. Mailing address: Division of Medical Genetics, Box 357720, University of Washington, Seattle, WA 98195. Phone: (206) 221-3973. Fax: (206) 685-8675. E-mail: lieber00@u.washington.edu.
Present address: Division of Human Gene Therapy, Department of Medicine, Gene Therapy Center, University of Alabama at Birmingham, Birmingham, Ala.
ISSN:0022-538X
1098-5514
DOI:10.1128/JVI.78.18.10009-10022.2004