Single-Nucleotide Polymorphisms of Growth Hormone Gene and Its Relationship with Growth Traits in Black Bengal Goats

• Published in: Animals (Basel) Vol. 14; no. 6; p. 834
• Main Authors: Buranakarl, Chollada, Chamsuwan, Sumonwan, Thammacharoen, Sumpun, Ratchakom, Panupat, Chuaypen, Natthaya
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 08.03.2024; MDPI
• Subjects: average daily gain; Bengal (goat breed); Birth weight; Black Bengal goat; chest; Dairy cattle; Farms; Genes; genotype; Genotype & phenotype; Goats; growth hormone gene; Growth hormones; growth traits; Insulin-like growth factors; litter size; males; Metabolism; Metabolites; Polymorphism; Single nucleotide polymorphisms; single-nucleotide polymorphism; Somatotropin; Thailand; Weaning; Thailand; Canada; India; Bangladesh; Black Bengal goat; growth hormone gene; growth traits; single-nucleotide polymorphism
• ISSN: 2076-2615; 2076-2615
• DOI: 10.3390/ani14060834

The single-nucleotide polymorphisms (SNPs) of the growth hormone (GH) gene could be related to growth traits, particularly in farm animals. This study aimed to identify the SNPs of the GH gene (A781G and A1575G) in Black Bengal (BB) goats in Thailand. Seventy-seven BB goats of both sexes were recruited, and their genotypes were identified. Preweaning growth at birth (weight, W0; height, H0; length, L0; and chest girth, C0) and at 10 weeks postpartum (W10, H10, L10, and C10), including average daily gain (ADG) at 0–4 weeks (ADG0–4W), 4–8 weeks (ADG4–8W), and 8–12 weeks (ADG8–12W), was compared among the different genotypes in goats born from twin litter-size dams. The results showed one genotype, CC, for A1575G and three genotypes, AA, AB, and BB, for A781G. The AA gene had significantly higher W10 than AB (p < 0.05) and BB (p < 0.05). The AA had significantly higher L10 than AB (p < 0.05), while C10 was only higher in male goats (p < 0.01). The ADG4–8W of the AA genotype was significantly higher than the BB genotype (p < 0.01). We came to the conclusion that A781G is associated with growth traits during the preweaning period, while the AA genotype showed better performance than the other genotypes.