Dynamic interpersonal neural synchronization underlying pain‐induced cooperation in females

• Published in: Human brain mapping Vol. 40; no. 11; pp. 3222 - 3232
• Main Authors: Wang, Chenbo, Zhang, Tingyu, Shan, Zhoukuidong, Liu, Jieqiong, Yuan, Di, Li, Xianchun
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.08.2019
• Subjects: Adolescent; Brain - diagnostic imaging; Care and treatment; Cooperation; Cooperative Behavior; Cortex (parietal); Female; Females; functional near‐infrared spectroscopy; Functional Neuroimaging; Humans; hyperscanning; interpersonal neural synchronization; Interpersonal Relations; Nerve Net - diagnostic imaging; Neural networks; Pain; Pain - diagnostic imaging; Pain - psychology; Pain Measurement; Prefrontal cortex; Social aspects; Social factors; Social interaction; Spectroscopy, Near-Infrared; Synchronism; Synchronization; Young Adult; pain; functional near-infrared spectroscopy; hyperscanning; cooperation; interpersonal neural synchronization
• ISSN: 1065-9471; 1097-0193; 1097-0193
• DOI: 10.1002/hbm.24592

Individuals in pain are motivated to be cooperative in social interaction. Yet, there has been little research on how pain dynamically affects cooperation at a neural level. The present study investigated the cooperative behavior under acute physical pain by asking dyads to complete three blocks of button‐press cooperative task, while neural activities were recorded simultaneously on each subject by the fNIRS‐based hyperscanning. Results showed that individuals in pain improved their cooperation rate across task blocks. Accordingly, increased interpersonal neural synchronization (INS) was found at the left prefrontal cortex in second block, whereas increased INS was found at the right prefrontal cortex and the right parietal cortex in third block compared to the first block. Moreover, the change of INS in right parietal cortex was positively correlated with subjective pain rating in the pain treatment group. In addition, dynamic interpersonal neural networks were identified in painful condition with increasing frontoparietal networks across time. By uncovering dissociative neural processes involved in how pain affects cooperation in social interaction, the present work provides the first interbrain evidence to highlight the sociality of pain on social interaction in perspective of motivational aspect of pain.